Teot L, Arnal F, Humeau C, Vannereau H, Pous J G
C R Seances Soc Biol Fil. 1985;179(3):365-70.
Epiphyseal bone transplantations including growth area have been extensively studied experimentally in different animals and applied in children for several decades. Results were unpredictable and the amount of growth obtained with the graft could get 50 per cent of the normal. Development of microsurgical techniques has determined new possibilities of epiphyseal transfer with the respect of the epiphyseal vascularization. Growth plate germinal cell division is directly related to the epiphyseal vascular respect. In a large multifacetted program we could successively determine the vascular patterns of the donor site areas and then utilized different grafts in some experimental situations reproducing the clinical pathology in children, like hip dysplasia or epiphyseal defects after resection for tumor or infection. Results demonstrate that the main problem, in epiphyseal transplantation, is not vascular but mechanical. Further studies have to be done in this direction.
包括生长区域的骨骺骨移植已经在不同动物身上进行了广泛的实验研究,并在儿童中应用了几十年。结果难以预测,移植获得的生长量可达正常量的50%。显微外科技术的发展确定了在骨骺血管化方面进行骨骺转移的新可能性。生长板生发细胞分裂与骨骺血管状况直接相关。在一个大型多方面的项目中,我们可以相继确定供体部位的血管模式,然后在一些实验情况下使用不同的移植物,再现儿童的临床病理情况,如髋关节发育不良或因肿瘤或感染切除后的骨骺缺损。结果表明,骨骺移植中的主要问题不是血管问题,而是机械问题。必须在这个方向上进一步开展研究。