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骨骺板微血管移植:利用同种异体供体材料的研究

Microvascular transplantation of epiphyseal plates: studies utilizing allograft donor material.

作者信息

Boyer Martin I, Bowen C Vaughan A

机构信息

Washington University School of Medicine, 1 Barnes-Jewish Hospital Plaza, Suite 11300, West Pavilion, St. Louis, MO 63110, USA.

出版信息

Orthop Clin North Am. 2007 Jan;38(1):103-8, vii. doi: 10.1016/j.ocl.2006.10.002.

Abstract

Compromised function of an epiphyseal plate caused by trauma, tumor, infection, or congenital malformation can result in significant musculoskeletal deformity. Techniques used to correct or minimize the extent of these deformities include autogenous or allogeneic cancellous bone grafts, nonvascularized cortical allografts, vascularized bone and composite tissue transfers, and distraction osteogenesis. These solutions are not ideal for children because they do not adequately address the actively growing nature of the extremity. Microvascular techniques have enabled the experimental transplantation of vascularized epiphyseal plates with high levels of postoperative viability and subsequent growth and offer a potential advantage over conventional treatments.

摘要

由创伤、肿瘤、感染或先天性畸形引起的骺板功能受损可导致严重的肌肉骨骼畸形。用于纠正或最小化这些畸形程度的技术包括自体或异体松质骨移植、非血管化皮质异体骨移植、血管化骨和复合组织移植以及牵张成骨术。这些解决方案对儿童并不理想,因为它们没有充分考虑到肢体的持续生长特性。微血管技术已使带血管骺板的实验性移植成为可能,术后其存活能力、后续生长能力较高,与传统治疗方法相比具有潜在优势。

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