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丹麦成年人中,遵循丹麦基于食物的膳食指南与心血管代谢风险因素之间的关联:DIPI 研究。

Associations between adherence to the Danish Food-Based Dietary Guidelines and cardiometabolic risk factors in a Danish adult population: the DIPI study.

机构信息

1Division of Diet, Disease Prevention and Toxicology,National Food Institute,Technical University of Denmark,2800 Kgs. Lyngby,Denmark.

2Danish Cancer Society,Section for Statistics and Pharmaco-Epidemiology,2100 Copenhagen,Denmark.

出版信息

Br J Nutr. 2018 Mar;119(6):664-673. doi: 10.1017/S0007114517003695. Epub 2018 Jan 21.

DOI:10.1017/S0007114517003695
PMID:29352831
Abstract

Diet is recognised as one modifiable lifestyle factor for ischaemic heart disease (IHD). We aimed at investigating the associations between adherence to the Danish Food-Based Dietary Guidelines (FBDG) indicated by a Dietary Quality Index (DQI) and selected cardiometabolic risk factors in a cross-sectional study with 219 Danish adult participants (59 %women; age 31-65years) with a minimum of one self-rated risk marker of IHD. Information regarding diet was obtained using web-based dietary assessment software and adherence to the Danish FBDG was expressed by a DQI calculated from 5 food and nutrient indicators (whole grain, fish, fruit and vegetables, energy from saturated fat and from added sugar). Background information, blood samples and anthropometrics were collected and blood pressure was measured. Linear regression analyses were used to evaluate the association between DQI and cardiometabolic risk factors. DQI was inversely associated with LDL:HDL ratio and TAG (-0·089 per unit; 95 % CI -0·177, -0·002 and -5 % per unit; 95 % CI -9, 0, respectively) and positively associated with HDL-cholesterol (0·047 mmol/l per unit; 95 % CI 0·007, 0·088). For men, DQI was inversely associated with BMI (-3 %per unit; 95 % CI -5, -1), trunk fat (-1 % per unit; 95 % CI -2, -1), high-sensitivity C-reactive protein (-30 % per unit; 95 % CI -41, -16 %), HbA1c (-0·09 % per unit; 95 % CI -0·14, -0·04), insulin (-13 % per unit; 95 % CI -19, -7) and homoeostatic model assessment-insulin resistance (-14 % per unit; 95 % CI -21, -7). In women, DQI was positively associated with systolic blood pressure (2·6 mmHg per unit; 95 % CI 0·6, 4·6). In conclusion, higher adherence to the current Danish FBDG was associated with a more beneficial cardiometabolic risk profile in a Danish adult population with a minimum of one self-rated risk factor for IHD.

摘要

饮食被认为是缺血性心脏病(IHD)的一种可改变的生活方式因素。我们旨在研究丹麦基于食物的膳食指南(FBDG)的依从性与选定的心血管代谢风险因素之间的关联,该研究是一项横断面研究,纳入了 219 名丹麦成年参与者(59%为女性;年龄 31-65 岁),他们至少有一个自评的 IHD 风险标志物。使用基于网络的膳食评估软件获取有关饮食的信息,并通过从 5 个食物和营养素指标(全谷物、鱼类、水果和蔬菜、饱和脂肪和添加糖提供的能量)计算得出的膳食质量指数(DQI)来表示对丹麦 FBDG 的依从性。收集背景信息、血液样本和人体测量数据,并测量血压。使用线性回归分析评估 DQI 与心血管代谢风险因素之间的关联。DQI 与 LDL:HDL 比值和 TAG 呈负相关(每单位 -0.089;95%CI-0.177,-0.002 和 -5%;95%CI-9,0),与 HDL-胆固醇呈正相关(每单位 0.047mmol/L;95%CI0.007,0.088)。对于男性,DQI 与 BMI(每单位-3%;95%CI-5,-1)、躯干脂肪(每单位-1%;95%CI-2,-1)、高敏 C 反应蛋白(每单位-30%;95%CI-41,-16%)、HbA1c(每单位-0.09%;95%CI-0.14,-0.04)、胰岛素(每单位-13%;95%CI-19,-7)和稳态模型评估胰岛素抵抗(每单位-14%;95%CI-21,-7)呈负相关。在女性中,DQI 与收缩压呈正相关(每单位 2.6mmHg;95%CI0.6,4.6)。总之,在丹麦成年人中,对当前丹麦 FBDG 的依从性越高,与至少有一个自评 IHD 风险因素的个体的心血管代谢风险特征越有利。

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