Ye Xi-Qian, Shi Min, Huang Jian-Hua, Chen Xue-Xin
State Key Lab of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insect Pests, Institute of Insect Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
State Key Lab of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insect Pests, Institute of Insect Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
Dev Comp Immunol. 2018 Jun;83:124-129. doi: 10.1016/j.dci.2018.01.007. Epub 2018 Jan 17.
Polydnaviruses (PDVs) are obligatory symbionts with parasitoid wasps. The PDV virions are produced solely in wasp (the primary host) calyx cells. They are injected into caterpillar hosts (the secondary host) during parasitoid oviposition, where they express irreplaceable actions to ensure survival and development of wasp larvae. Some of PDV gene products suppress host immune responses while others alter host growth, metabolism or endocrine system. Here, we treat new findings on PDV gene products and their action on immunity within secondary hosts.
多DNA病毒（PDVs）是寄生蜂的专性共生体。PDV病毒粒子仅在黄蜂（主要宿主）的萼细胞中产生。在寄生蜂产卵时，它们被注入毛虫宿主（次要宿主）体内，在那里它们发挥着不可替代的作用，以确保黄蜂幼虫的存活和发育。一些PDV基因产物会抑制宿主的免疫反应，而其他产物则会改变宿主的生长、代谢或内分泌系统。在这里，我们探讨了关于PDV基因产物及其在次要宿主免疫方面作用的新发现。
