Lucaire Vincent, Schwartz Jean-Jacques, Delhomme Olivier, Ocampo-Torres Ruben, Millet Maurice
Institut de Chimie et Procédés pour l'Energie, l'Environnement et la Santé (ICPEES UMR 7515 CNRS, Université de Strasbourg), 1 rue Blessig, 67084, Strasbourg Cedex, France.
Laboratoire de Chimie et de Physique, Approche Multi-Echelles des Milieux Complexes (LCP-A2MC), Université de Lorraine, 1 boulevard Arago, 57078, Metz Cedex 3, France.
Anal Bioanal Chem. 2018 Mar;410(7):1955-1963. doi: 10.1007/s00216-018-0862-8. Epub 2018 Jan 20.
Monitoring the levels of aliphatic and aromatic amines (AA) in indoor air is important to protect human health because of exposure to these compounds through diet and inhalation. A sampling and analytical method using XAD-2 cartridges and gas chromatography coupled to mass spectrometry used for assessing 25 AA in different smoking and non-smoking indoor environment was developed. After sampling and delivering 1 m of air (6-8 h sampling), an adsorbent was ultrasonically extracted with acetonitrile, concentrated to 1 mL and diluted in 25 mL of water (pH = 9; 5% NaCl), and then extracted for 40 min at 80 °C using a divinylbenzene/carboxen/polydimethylsiloxane (DVB/CAR/PDMS) fiber and injected in a GC/MS system. With this method, 22 of the 25 AA can be analyzed with detection limits up to five times lower than that of classic liquid injection. Benzylamine, 3-aminophenol, and 4-aminophenol were not detected with the solid-phase micro-extraction (SPME) method. It can be assumed that aminophenols required a derivatization step for their analysis by GC as these molecules were not detected regardless of the injection mode used. Graphical abstract Analysis of aromatic amines in indoor air by SPME-GC/MS.
监测室内空气中脂肪族和芳香族胺（AA）的含量对于保护人类健康很重要，因为人们会通过饮食和吸入接触到这些化合物。开发了一种使用XAD-2柱和气相色谱-质谱联用的采样和分析方法，用于评估不同吸烟和非吸烟室内环境中的25种AA。采样并采集1立方米空气（6-8小时采样）后，用乙腈对吸附剂进行超声萃取，浓缩至1毫升并稀释于25毫升水中（pH = 9；5%氯化钠），然后使用二乙烯基苯/碳分子筛/聚二甲基硅氧烷（DVB/CAR/PDMS）纤维在80℃下萃取40分钟，并注入气相色谱/质谱系统。用这种方法，可以分析25种AA中的22种，检测限比传统液体进样低五倍。采用固相微萃取（SPME）方法未检测到苄胺、3-氨基苯酚和4-氨基苯酚。可以假定氨基酚通过气相色谱分析需要衍生化步骤，因为无论使用何种进样模式都未检测到这些分子。图形摘要：通过SPME-GC/MS分析室内空气中的芳香胺。
