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高血压、糖尿病和肥胖与社区居住老年人较低的认知能力相关:来自FIBRA研究的数据。

Hypertension, diabetes and obesity are associated with lower cognitive performance in community-dwelling elderly: Data from the FIBRA study.

作者信息

de Oliveira Monalisa Fernanda Bocchi, Yassuda Mônica Sanches, Aprahamian Ivan, Neri Anita Liberalesso, Guariento Maria Elena

机构信息

Post-Graduate Program in Gerontology - Faculty of Medical Sciences, State University of Campinas - Unicamp, Campinas, SP, Brazil.

School of Arts, Sciences and Humanities, University of São Paulo, São Paulo, Brazil.

出版信息

Dement Neuropsychol. 2017 Oct-Dec;11(4):398-405. doi: 10.1590/1980-57642016dn11-040009.

Abstract

BACKGROUND

Systemic hypertension (SH), diabetes mellitus (DM) and abdominal obesity may negatively impact cognitive performance.

OBJECTIVE

To evaluate the association between SH, DM and abdominal obesity and cognitive performance among cognitively unimpaired elderly.

METHODS

A cross-sectional study of individuals aged 65+ from seven Brazilian cities was conducted. SH and DM diagnoses were self-reported and abdominal circumference was objectively measured. Individuals who scored below the education-adjusted cutoff scores on the Mini-Mental State Examination (MMSE) were excluded.

RESULTS

Among 2,593 elderly, 321 (12.38%) had SH, DM and abdominal obesity concomitantly (Group I) and 421 (16.23%) had none of the three diseases (Group II). Group I had a higher proportion of individuals that were women, aged 70-74 years, illiterate and with lower income. Group I had a higher number of participants with low cognitive performance (28.04% vs. 17.58% in Group II). Variables associated with poor cognitive performance were: female gender (OR: 2.43, < 0.001); and lower education (OR: 0.410, < 0.001). The presence of the three diseases and age were not significant in the education-adjusted model.

CONCLUSION

There was an association between cognition and the presence of SH, DM and obesity. However, education seems to be decisive in determining cognitive performance in the presence of these three conditions.

摘要

背景

系统性高血压(SH)、糖尿病(DM)和腹型肥胖可能会对认知能力产生负面影响。

目的

评估认知功能未受损的老年人中SH、DM和腹型肥胖与认知能力之间的关联。

方法

对来自巴西七个城市的65岁及以上个体进行了一项横断面研究。SH和DM的诊断通过自我报告,腹围通过客观测量。在简易精神状态检查表(MMSE)中得分低于教育调整后的临界分数的个体被排除。

结果

在2593名老年人中,321人(12.38%)同时患有SH、DM和腹型肥胖(第一组),421人(16.23%)三种疾病均未患(第二组)。第一组中女性、年龄在70 - 74岁、文盲且收入较低的个体比例更高。第一组认知能力较低的参与者数量更多(28.04%对第二组的17.58%)。与认知能力差相关的变量为:女性(比值比:2.43,<0.001);以及较低的教育程度(比值比:0.410,<0.001)。在教育调整模型中,三种疾病的存在和年龄并不显著。

结论

认知与SH、DM和肥胖的存在之间存在关联。然而,在这三种情况存在时,教育似乎是决定认知能力的关键因素。

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本文引用的文献

1
Metabolically Healthy Obesity and the Risk of Cardiovascular Disease in the Elderly Population.
PLoS One. 2016 Apr 21;11(4):e0154273. doi: 10.1371/journal.pone.0154273. eCollection 2016.
4
Cardiovascular risk profile in women and dementia.
J Alzheimers Dis. 2014;42 Suppl 4:S353-63. doi: 10.3233/JAD-141629.
5
Understanding and preventing the development of post-stroke dementia.
Expert Rev Neurother. 2014 Sep;14(9):1067-77. doi: 10.1586/14737175.2014.947276. Epub 2014 Aug 8.
6
Potential for primary prevention of Alzheimer's disease: an analysis of population-based data.
Lancet Neurol. 2014 Aug;13(8):788-94. doi: 10.1016/S1474-4422(14)70136-X.
7
Brain metabolic dysfunction at the core of Alzheimer's disease.
Biochem Pharmacol. 2014 Apr 15;88(4):548-59. doi: 10.1016/j.bcp.2013.12.012. Epub 2013 Dec 28.
9
The global prevalence of dementia: a systematic review and metaanalysis.
Alzheimers Dement. 2013 Jan;9(1):63-75.e2. doi: 10.1016/j.jalz.2012.11.007.

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