韩国既往诊断为淋巴丝虫病患者的随访研究。
Follow-up Study of Patients Previously Diagnosed with Lymphatic Filariasis in Korea.
作者信息
Cheun Hyeng Il, Shin Hee Eun, Ma Da Won, Hong Sung Hee, Kim Tae Yun, Lee Sang Eun, Ju JungWon, Park Yun-Kyu, Kim Tong-Soo, Cho Shin Hyeong
机构信息
Division of Malaria and Parasitic Diseases, National Research Institute of Health, Korea Centers for Diseases Control and Prevention, Osong, Korea.
Department of Parasitology, Inha University School of Medicine, Incheon, Korea.
出版信息
Osong Public Health Res Perspect. 2017 Dec;8(6):421-424. doi: 10.24171/j.phrp.2017.8.6.10. Epub 2017 Dec 31.
OBJECTIVES
Korea was an endemic area for lymphatic filariasis (LF), caused by the nematode parasite , until the 1970s. The World Health Organization recognized Korea as LF-free in June 2008. However, it is necessary to confirm that patients that have had LF in the past still test negative, to prevent the re-emergence of LF in Korea.
METHODS
We followed up a total of 83 patients who had been diagnosed with LF between 2002 and 2010 in endemic LF areas.
RESULTS
Fifty-two of the 83 subjects were negative for LF, whereas 31 subjects had re-located to a different city or province, were dead, or were unaccounted for. Most subjects with negative test results still exhibited edema in the legs or the arms, and some complained of redness and swelling in the legs or ankle joints. However, we found that these symptoms were due to diseases other than LF.
CONCLUSION
In this follow-up study, we did not find any evidence indicating the potential re-emergence of LF in Korea.
目的
直到20世纪70年代，韩国一直是由线虫寄生虫引起的淋巴丝虫病（LF）的流行地区。2008年6月，世界卫生组织认定韩国无淋巴丝虫病。然而，有必要确认过去曾患淋巴丝虫病的患者检测结果仍为阴性，以防止淋巴丝虫病在韩国再次出现。
方法
我们对2002年至2010年期间在淋巴丝虫病流行地区被诊断为淋巴丝虫病的83名患者进行了随访。
结果
83名受试者中有52名淋巴丝虫病检测呈阴性，而31名受试者已搬到其他城市或省份、死亡或下落不明。大多数检测结果为阴性的受试者仍有腿部或手臂水肿，一些人抱怨腿部或踝关节发红肿胀。然而，我们发现这些症状是由淋巴丝虫病以外的疾病引起的。
结论
在这项随访研究中，我们没有发现任何证据表明淋巴丝虫病有可能在韩国再次出现。
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