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[冠状动脉狭窄的再扩张。对长期结果的影响]

[Redilatation of coronary stenoses. Effect on long-term results].

作者信息

Meier B

出版信息

Herz. 1985 Dec;10(6):321-6.

PMID:2935467
Abstract

Subsequent to percutaneous transluminal coronary angioplasty (PTCA), with a primary success rate of between 84 and 94%, restenosis is reported to occur in 17 to 47%. Redilatation has been considered in about 30% of dilated patients and carried out in 20%. The experience presented is based on 608 consecutive patients who underwent PTCA at Emory University in Atlanta as well as 350 consecutive patients treated at the University of Genf. In general, the primary success rate of repeated PTCA is reported to be significantly better. Based on our data, the primary success of redilatation was 97%, as compared with an 87% success rate on initial dilatation. Associated with second and third dilatations, there is a substantially lower incidence of complications; in our patients, obstructive dissections occurred in 1% as compared with 7% at the time of initial dilatation and myocardial infarction was not observed (as compared with 1% initially). Emergency bypass surgery was required in only 1% as compared with 5% at initial dilatation. With regard to longterm results, the data reported shows some differences. While most of the figures indicate a rate of restenosis comparable to that seen after initial dilatation, a higher incidence of restenosis has been observed. In our patients, the rate of restenosis after repeat PTCA was essentially similar to that seen after initial PTCA; overall, however, that associated with LAD stenoses was notably higher. On use of redilatation, 78% of all patients, instead of only 63% after successful initial dilatation, had longterm benefits from this mode of therapy.

摘要

经皮腔内冠状动脉成形术(PTCA)后,其初始成功率在84%至94%之间,据报道再狭窄发生率为17%至47%。约30%的接受扩张治疗的患者考虑进行再次扩张,其中20%实施了再次扩张。这里介绍的经验基于在亚特兰大的埃默里大学接受PTCA的608例连续患者以及在日内瓦大学接受治疗的350例连续患者。一般而言,据报道重复PTCA的初始成功率明显更高。根据我们的数据,再次扩张的初始成功率为97%,而初次扩张的成功率为87%。与第二次和第三次扩张相关的并发症发生率大幅降低;在我们的患者中,阻塞性夹层分离的发生率为1%,而初次扩张时为7%,且未观察到心肌梗死(初次时为1%)。紧急搭桥手术仅需1%,而初次扩张时为5%。关于长期结果,所报告的数据显示出一些差异。虽然大多数数据表明再狭窄率与初次扩张后相似,但已观察到再狭窄发生率更高。在我们的患者中,重复PTCA后的再狭窄率与初次PTCA后基本相似;然而总体而言,与左前降支狭窄相关的再狭窄率明显更高。使用再次扩张后,所有患者中有78%从这种治疗方式中获得了长期益处,而初次扩张成功后只有63%的患者有此获益。

相似文献

1
[Redilatation of coronary stenoses. Effect on long-term results].[冠状动脉狭窄的再扩张。对长期结果的影响]
Herz. 1985 Dec;10(6):321-6.
2
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[Quantitative coronary angiography before and after PTCA. Rate of restenosis, analysis of modifying factors].[经皮腔内冠状动脉成形术前后的定量冠状动脉造影。再狭窄率及相关影响因素分析]
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