Tan Yuyong, Tan Linna, Lu Jiaxi, Huo Jirong, Liu Deliang
Department of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha 410011, China.
Transl Gastroenterol Hepatol. 2017 Dec 19;2:115. doi: 10.21037/tgh.2017.12.03. eCollection 2017.
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in the gastrointestinal tract, and about 60% of them are found in the stomach. With the widespread application of endoscopy and endoscopic ultrasonography (EUS), more and more gastric GISTs are being found in an early stage (with a relative small diameter and no metastasis), giving the chance of complete resection. Endoscopic resection such as endoscopic band ligation (EBL), endoscopic submucosal dissection (ESD), endoscopic submucosal excavation (ESE), endoscopic full-thickness resection (EFTR) and submucosal tunneling endoscopic resection (STER), is a minimally invasive method compared with the conventional surgical approaches (open or laparoscopic), and has been demonstrated to be safe and effective for treating gastric GISTs. This review summarizes the recent advances on endoscopic resection of gastric GISTs, aiming to provide a rational management strategy for gastric GISTs.
胃肠道间质瘤(GISTs)是胃肠道最常见的间叶性肿瘤,其中约60%发生于胃。随着内镜检查和内镜超声(EUS)的广泛应用,越来越多的胃GISTs在早期被发现(直径相对较小且无转移),从而有机会进行完整切除。与传统手术方法(开放或腹腔镜手术)相比,内镜下切除如内镜下套扎术(EBL)、内镜黏膜下剥离术(ESD)、内镜黏膜下挖除术(ESE)、内镜全层切除术(EFTR)和黏膜下隧道内镜切除术(STER)是一种微创方法,并且已被证明对治疗胃GISTs安全有效。本综述总结了胃GISTs内镜下切除的最新进展,旨在为胃GISTs提供合理的管理策略。