Bronze Sérgio, Botto Inês, Ruivo Leonor, Oliveira Tiago, Moura Miguel, Ribeiro Luís Carrilho, Correia Luís
Gastroenterology and Hepatology Department, Unidade Local de Saúde Santa Maria, Lisbon, Portugal.
Faculty of Medicine, University of Lisbon, Lisbon, Portugal.
ACG Case Rep J. 2024 Nov 16;11(11):e01553. doi: 10.14309/crj.0000000000001553. eCollection 2024 Nov.
Gastric glomus tumor (GGT) is a rare mesenchymal neoplasm, that is usually asymptomatic. Although benign, malignant transformation has been reported. A 59-year-old man presented with dyspepsia refractory to treatment with proton-pump inhibitor over 6 months. Esophagogastroduodenoscopy revealed a 30 mm subepithelial lesion in the distal gastric antrum, in contact with the pylorus, but biopsies were nonspecific. Upper endoscopic ultrasound revealed a well-defined submucosal echogenic lesion measuring 30 × 20 mm, without muscularis propria involvement. A fine-needle aspiration biopsy showed GGT features. En bloc endoscopic resection was performed using the submucosal tunneling endoscopic resection technique. The histopathological study of the specimen confirmed the diagnosis of a GGT with free margins. The patient remains symptom-free after a 9-month follow-up. We highlight the rare diagnosis of GGT and the possibility of curative en bloc endoscopic resection with submucosal tunneling endoscopic resection.
胃血管球瘤（GGT）是一种罕见的间叶性肿瘤，通常无症状。尽管为良性，但已有恶变的报道。一名59岁男性出现消化不良症状，使用质子泵抑制剂治疗6个月以上无效。食管胃十二指肠镜检查发现胃窦远端有一个30毫米的上皮下病变，与幽门相连，但活检结果不具有特异性。上消化道内镜超声显示一个边界清晰的黏膜下高回声病变，大小为30×20毫米，未累及固有肌层。细针穿刺活检显示具有GGT特征。采用黏膜下隧道内镜切除术进行整块内镜切除。标本的组织病理学研究证实诊断为切缘阴性的GGT。随访9个月后，患者无症状。我们强调了GGT的罕见诊断以及通过黏膜下隧道内镜切除术进行根治性整块内镜切除的可能性。
