Cheng Bing Qian, Du Chen, Li Hui Kai, Chai Ning Li, Linghu En Qiang
Department of Gastroenterology and Hepatology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
J Dig Dis. 2024 Sep-Oct;25(9-10):550-558. doi: 10.1111/1751-2980.13217. Epub 2023 Sep 14.
Surgical resection is regarded as the main modality for the treatment of gastrointestinal stromal tumors (GISTs). With the advancement of endoscopic techniques and the introduction of super minimally invasive surgery (SMIS), endoscopic resection has been an alternative option to surgery. Recently, various endoscopic resection techniques have been used for the treatment of GISTs, including endoscopic submucosal dissection (ESD), endoscopic submucosal excavation (ESE), endoscopic full-thickness resection (EFR), submucosal tunneling endoscopic resection (STER), and laparoscopic and endoscopic cooperative surgery (LECS). Studies on the safety and efficacy of the endoscopic treatment of GISTs have emerged in recent years. Endoscopic resection techniques have demonstrated to be effective and safe for the treatment of GISTs. However, there is currently no consensus on the optimal follow-up strategy and the appropriate cut-off value of tumor size for endoscopic resection. In this review we discussed the indications, preoperative preparation, procedures, efficacy, safety, postoperative evaluation, follow-up, and perspectives of endoscopic resection modalities for GISTs.
手术切除被视为治疗胃肠道间质瘤（GISTs）的主要方式。随着内镜技术的进步以及超微创手术（SMIS）的引入，内镜切除已成为手术的一种替代选择。近年来，各种内镜切除技术已被用于治疗GISTs，包括内镜黏膜下剥离术（ESD）、内镜黏膜下挖除术（ESE）、内镜全层切除术（EFR）、黏膜下隧道内镜切除术（STER）以及腹腔镜与内镜联合手术（LECS）。近年来出现了关于内镜治疗GISTs安全性和有效性的研究。内镜切除技术已被证明对治疗GISTs有效且安全。然而，目前对于内镜切除的最佳随访策略以及合适的肿瘤大小截断值尚无共识。在本综述中，我们讨论了GISTs内镜切除方式的适应证、术前准备、操作过程、疗效、安全性、术后评估、随访及展望。
