钴（II）催化的芳香酰胺与碘的螯合辅助C-H碘化反应
Cobalt(ii)-catalyzed chelation-assisted C-H iodination of aromatic amides with I.
作者信息
Kommagalla Yadagiri, Yamazaki Ken, Yamaguchi Takuma, Chatani Naoto
机构信息
Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
出版信息
Chem Commun (Camb). 2018 Feb 1;54(11):1359-1362. doi: 10.1039/c7cc08457a.
PMID:29354844
Abstract
The cobalt-catalyzed chelation-assisted iodination of aromatic amides using molecular I as an iodinating reagent is reported. 8-Amino-5-chloroquinoline functions as an efficient directing group. This mild and air stable catalytic system shows a wide functional group tolerance and improved synthetic accessibility.
摘要
报道了使用分子碘作为碘化试剂，钴催化的芳香酰胺螯合辅助碘化反应。8-氨基-5-氯喹啉作为一种有效的导向基团。这种温和且对空气稳定的催化体系具有广泛的官能团耐受性和更高的合成可及性。
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