钴催化的芳香酰胺与未活化烯烃的螯合辅助C-H烯丙基化反应。
Cobalt-catalyzed chelation assisted C-H allylation of aromatic amides with unactivated olefins.
作者信息
Yamaguchi Takuma, Kommagalla Yadagiri, Aihara Yoshinori, Chatani Naoto
机构信息
Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
出版信息
Chem Commun (Camb). 2016 Aug 9;52(66):10129-32. doi: 10.1039/c6cc05330k.
PMID:27444652
Abstract
The cobalt-catalyzed chelation assisted ortho C-H allylation of aromatic amides with unactivated aliphatic alkenes is reported. The reaction proceeds in air under mild reaction conditions, providing allylated products in good to excellent yields with high E-selectivities. This operationally simple method shows a high functional group tolerance.
摘要
报道了钴催化的芳族酰胺与未活化脂肪族烯烃的邻位C-H烯丙基化反应。该反应在空气中温和的反应条件下进行，以良好至优异的产率提供具有高E-选择性的烯丙基化产物。这种操作简单的方法显示出高官能团耐受性。
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