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[针刺治疗慢性偏头痛的神经可塑性机制]

[Mechanism of neural plasticity of acupuncture on chronic migraine].

作者信息

Xu Xiaobai, Liu Lu, Zhao Luopeng, Qu Zhengyang, Zhu Yupu, Zhang Yajie, Wang Linpeng

机构信息

Center of Acupuncture and Moxibustion, Beijing TCM Hospital of Capital Medical University, Beijing 100010, China.

Beijing University of CM.

出版信息

Zhongguo Zhen Jiu. 2017 Oct 12;37(10):1134-40. doi: 10.13703/j.0255-2930.2017.10.029.

DOI:10.13703/j.0255-2930.2017.10.029
PMID:29354986
Abstract

Chronic migraine is one of neurological disorders with high rate of disability, but sufficient attention has not been paid in this field. A large number of clinical studies have shown traditional Chinese acupuncture is a kind of effective treatment with less side effects. Through the analysis of literature regarding acupuncture and migraine published from 1981 to 2017 in CNKI and PubMed databases, the mechanism of neural plasticity of acupuncture on chronic migraine was explored. It was believed the progress of chronic migraine involved the changes of neural plasticity in neural structure and function, and the neural plasticity related with neural sensitization during the process of chronic migraine was discussed from three aspects of electrophysiology, molecular chemistry and radiography. Acupuncture could treat and prevent chronic migraine via the mechanism of neural plasticity, but there was no related literature, hindering the further spreading and development of acupuncture for chronic migraine.

摘要

慢性偏头痛是致残率较高的神经系统疾病之一,但该领域尚未得到足够重视。大量临床研究表明,中医针灸是一种疗效显著且副作用较小的治疗方法。通过分析中国知网(CNKI)和美国国立医学图书馆生物医学期刊数据库(PubMed)中1981年至2017年发表的关于针灸与偏头痛的文献,探讨了针灸治疗慢性偏头痛的神经可塑性机制。认为慢性偏头痛的进展涉及神经结构和功能的神经可塑性变化,并从电生理学、分子化学和影像学三个方面探讨了慢性偏头痛过程中与神经敏化相关的神经可塑性。针灸可通过神经可塑性机制治疗和预防慢性偏头痛,但尚无相关文献报道,这阻碍了针灸治疗慢性偏头痛的进一步推广和发展。

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