Pan Shimin, Li Jinxiang, Zhang Xi, Li Ying, Yan Jie, Zhang Wei, Hu Sha
Department of Acupuncture and Moxibustion, the First Affiliated Hospital of Hunan University of CM, Changsha 410007, China; Graduate School of Hunan University of CM, Changsha 410208.
Department of Acupuncture and Moxibustion, the First Affiliated Hospital of Hunan University of CM, Changsha 410007, China.
Zhongguo Zhen Jiu. 2017 Dec 12;37(12):1255-60. doi: 10.13703/j.0255-2930.2017.12.001.
To observe the clinical effects of the acupuncture regulating based on the compatibility of the five meridians and common western medication for gastroesophageal reflux disease with the disharmony between liver and stomach.
Sixty patients were divided into two groups according to non-erosive reflux disease (NERD) and reflux esophagitis (RE). Those in the two groups were randomly assigned into an observation group and a control group. There were 57 cases included (28 in the observation group with 2 dropping, 29 in the control group with 1 dropping). Based on the life care, patients in the observation group were treated with 30 min acupuncture regulating based on the compatibility of the five meridians at Zusanli (ST 36), Chongyang (ST 42), Weishu (BL 21), Zhongwan (CV 12), Xingjian (LR 2), Shaofu (HT 8), Dadun (LR 1), Taichong (LR 3), Ganshu (BL 18), Qimen (LR 14), Danzhong (CV 17), Zhongting (CV 16), three times a week. Patients in the control group were treated with rabeprazole orally. All the treatment was given for consecutive 8 weeks. The clinical symptom score was observed before and after treatment and 4 weeks after treatment. The effects were evaluated from 3 aspects, including the main symptoms, esophagitis improvement under gastroscope and total clinical symptoms.
After treatment and at follow-up, the symptom scores decreased in the two groups compared with those before treatment (all <0.05), with better improvement in the observation group at follow-up (<0.05). The symptom scores after treatment of the two types in the two groups decreased compared with those before treatment (all <0.05). The total effective rate of heartburn after treatment in the observation group was 82.1% (23/28), which was lower than 93.1% (27/29) of the control group (<0.05). The total effective rate of belching after treatment in the observation group was 94.1% (16/17), which was better than 75.0% (15/20) in the control group (<0.05). The total effective rate of the esophagitis improvement under gastroscope after treatment in the observation group was 75.0% (12/16), and that in the control group was 82.4% (14/17), without statistical significance (>0.05). The total effective rate of the clinical symptoms after treatment in the observation group was 82.1% (23/28), and that in the control group was 86.2% (25/29), without statistical significance (>0.05).
Acupuncture regulating based on compatibility of the five meridians can effectively improve clinical symptoms and inflammation under gastroscope for gastroesophageal reflux disease with the disharmony between liver and stomach. This treatment has a longer curative effect and a greater alleviation of belching.
观察基于五脉配伍的针刺调节法联合常用西药治疗肝胃不和型胃食管反流病的临床疗效。
将60例患者按非糜烂性反流病（NERD）和反流性食管炎（RE）分为两组，两组再随机分为观察组和对照组。共纳入57例（观察组28例，脱落2例；对照组29例，脱落1例）。在生活护理基础上，观察组采用基于五脉配伍的针刺调节法，针刺足三里（ST 36）、冲阳（ST 42）、胃俞（BL 21）、中脘（CV 12）、行间（LR 2）、少府（HT 8）、大敦（LR 1）、太冲（LR 3）、肝俞（BL 18）、期门（LR 14）、膻中（CV 17）、中庭（CV 16），每次30分钟，每周3次。对照组口服雷贝拉唑。所有治疗均连续进行8周。观察治疗前后及治疗后4周的临床症状评分，从主要症状、胃镜下食管炎改善情况和临床症状总积分3个方面进行疗效评价。
治疗后及随访时，两组症状评分均较治疗前下降（均P<0.05），随访时观察组改善更好（P<0.05）。两组两种类型治疗后症状评分均较治疗前下降（均P<0.05）。观察组治疗后烧心总有效率为82.1%（23/28），低于对照组的93.1%（27/29）（P<0.05）。观察组治疗后嗳气总有效率为94.1%（16/17），优于对照组的75.0%（15/20）（P<0.05）。观察组治疗后胃镜下食管炎改善总有效率为75.0%（12/16），对照组为82.4%（14/17），差异无统计学意义（P>0.05）。观察组治疗后临床症状总有效率为82.1%（23/28），对照组为86.2%（25/29），差异无统计学意义（P>0.05）。
基于五脉配伍的针刺调节法能有效改善肝胃不和型胃食管反流病的临床症状及胃镜下炎症，疗效持久，对嗳气缓解作用较大。
