Wang Ying-Ying, Xu Wei, Wang Xiao, Gao Wei, He Li, Su Yi, Du Xin
Hebei Provincial Hospital of TCM, Shijiazhuang 050011, China.
Xinle Municipal Hospital of TCM.
Zhongguo Zhen Jiu. 2020 Feb 12;40(2):137-41. doi: 10.13703/j.0255-2930.20190130-00034.
To verify the clinical effect of laryngopharyngeal reflux (LPR) treated with acupuncture at the acupoints composed on the base of theory of the ascending and the descending of .
A total of 84 patients of LPR were randomized into an observation group and a control group, 42 cases in each one. The conventional treatment was provided in the two groups. Additionally, in the control group, the medication was administered, i.e. esomeprazole tablets (20 mg, twice a day) and mosapride tablets (5 mg, three times a day), consecutively for 14 days. In the observation group, the oral medication was the same as the control group. Besides, acupuncture at the acupoints composed on the base of theory of the ascending and the descending of was supplemented. The acupoints were Tiantu (CV 22), Danzhong (CV 17), Zhongwan (CV 12), Zusanli (ST 36), Taichong (LR 3) and Neiguan (PC 6). The acupuncture treatment was given once a day, 5 times a week, consecutively for 10 times in 2 weeks (14 days in total). Before and after treatment, the reflux symptom index (RSI) score, the reflux finding score (RFS) and the time proportion of esophageal pH < 4 in 24 h were compared, and the therapeutic effect was evaluated in the two groups.
After treatment, RSI score, RFS, 24 h esophageal pH<4 time proportion were all reduced as compared with those before treatment in the two groups (<0.05). After treatment, RSI score, RFS, 24 h esophageal pH<4 time proportion in the observation group were lower than those in the control group (<0.05). The total effective rate was 92.9% (39/42) in the observation group, better than 71.4% (30/42) in the control group (<0.05).
On the base of the conventional treatment, acupuncture at the acupoints composed in compliance with the theory of the ascending and the descending of combined with western medication contribute to the recovery of gastrointestinal function, effectively control the laryngopharyngeal symptoms and physical signs. The therapeutic effect of this comprehensive therapy is better than the simple treatment with western medication.
验证基于升降理论组穴针刺治疗喉咽反流(LPR)的临床疗效。
将84例LPR患者随机分为观察组和对照组,每组42例。两组均给予常规治疗。此外,对照组给予药物治疗,即埃索美拉唑片(20mg,每日2次)和莫沙必利片(5mg,每日3次),连续服用14天。观察组口服药物与对照组相同。除此之外,加用基于升降理论组穴针刺治疗。穴位为天突(CV22)、膻中(CV17)、中脘(CV12)、足三里(ST36)、太冲(LR3)和内关(PC6)。针刺治疗每日1次,每周5次,2周内连续治疗10次(共14天)。比较两组治疗前后反流症状指数(RSI)评分、反流发现评分(RFS)及24小时食管pH<4的时间比例,并评价两组疗效。
治疗后,两组RSI评分、RFS、24小时食管pH<4时间比例均较治疗前降低(P<0.05)。治疗后,观察组RSI评分、RFS、24小时食管pH<4时间比例低于对照组(P<0.05)。观察组总有效率为92.9%(39/42),优于对照组的71.4%(30/42)(P<0.05)。
在常规治疗基础上,基于升降理论组穴针刺联合西药有助于胃肠功能恢复,有效控制喉咽症状及体征。该综合疗法的疗效优于单纯西药治疗。