Aiyekomogbon Joshua Oluwafemi, Igashi Joseph Bako, Lawan Reuben Omokafe, Bioku Muftau Jimoh, Ameadaji Musa
Department of Radiology, College of Health Sciences, University of Abuja, Abuja, Nigeria.
Department of Radiology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
Niger Postgrad Med J. 2017 Oct-Dec;24(4):210-216. doi: 10.4103/npmj.npmj_144_17.
Erectile dysfunction (ED) is an inability to achieve and maintain erectile rigidity sufficient for satisfactory sexual performance. It is either organic or psychogenic in origin. This study was aimed at establishing vasculogenic causes among patients being evaluated for ED using triplex Doppler Ultrasound.
This study was conducted at the Department of Radiology, Federal Medical Centre, Abuja, Nigeria from July 2015 to January 2017. Thirty-five consecutive patients with the clinical diagnosis of ED were evaluated with colour Doppler ultrasound scan using a high-frequency linear transducer. The penile scan was done before and after intracavernosal injection of 10-20 μg prostaglandin E1. The waveforms of cavernosal arteries (CAs) were obtained alternately using angle of inclination ≤60°. The spectral waveforms and peak systolic velocities (PSV) of the CA were documented at 5-min intervals, from 5 to 50 min.
PSV of CA varied between 19.5 and 104.4 cm/s (mean: 42.4 ± 17.6) among the entire patients and between 19.5 and 24.7 cm/s (mean: 21.9 ± 1.7) among patients with arteriogenic ED. Arteriogenic ED was found in six patients (17%), while venogenic ED was observed in ten patients, which constituted 29% of the entire participants. None had combined arteriogenic and venogenic ED. Peyronie's disease was observed in seven patients, and none of these had vasculogenic ED.
About 46% of the patients had vasculogenic ED. It is therefore imperative that patients with ED benefit from this safe, cheap and non-ionising diagnostic modality before initiating therapy as ED treatment is cause specific.
勃起功能障碍(ED)是指无法达到和维持足以实现满意性行为的勃起硬度。其病因要么是器质性的,要么是心因性的。本研究旨在利用经颅多普勒超声确定接受勃起功能障碍评估的患者中的血管源性病因。
本研究于2015年7月至2017年1月在尼日利亚阿布贾联邦医疗中心放射科进行。连续35例临床诊断为勃起功能障碍的患者使用高频线性换能器进行彩色多普勒超声扫描评估。在海绵体内注射10 - 20μg前列腺素E1之前和之后进行阴茎扫描。使用倾斜角度≤60°交替获取海绵体动脉(CA)的波形。在5至50分钟内,每隔5分钟记录CA的频谱波形和收缩期峰值速度(PSV)。
在所有患者中,CA的PSV在19.5至104.4cm/s之间(平均:42.4±17.6),在动脉源性勃起功能障碍患者中,PSV在19.5至24.7cm/s之间(平均:21.9±1.7)。6例患者(17%)被发现患有动脉源性勃起功能障碍,10例患者被观察到患有静脉源性勃起功能障碍,占全部参与者的29%。没有患者同时患有动脉源性和静脉源性勃起功能障碍。7例患者观察到佩罗尼氏病,这些患者中没有血管源性勃起功能障碍。
约46%的患者患有血管源性勃起功能障碍。因此,在开始治疗之前,勃起功能障碍患者必须受益于这种安全、廉价且非电离的诊断方式,因为勃起功能障碍的治疗是病因特异性的。