Li Susan S, Hayes Don, Tobias Joseph D, Morgan Wayne J, Tumin Dmitry
Department of Pediatrics, Nationwide Children's Hospital, Columbus, Ohio.
Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, Ohio.
Clin Respir J. 2018 May;12(5):1981-1988. doi: 10.1111/crj.12767. Epub 2018 Feb 9.
Low socioeconomic status is correlated with worse outcomes in patients with cystic fibrosis (CF). Whether insurance status impacts adherence to care in this population is unknown.
Patients ≥18 years old in the CF Foundation Patient Registry (2005-2013) were grouped based on reported annual insurance as private, public (Medicaid, Medicare or state medical assistance program), others or no insurance. Random effects logistic regression evaluated association between change in insurance status and annual use of recommended routine care.
A total of 18 358 patients contributed 94 690 years of data to the analysis. In descriptive analysis, adherence to recommended routine care (≥4 clinic visits, ≥4 respiratory cultures and ≥2 pulmonary function tests per year) and recommended chronic medications for those with moderate to severe lung disease (dornase alfa and inhaled tobramycin or aztreonam if Pseudomoas aeruginosa in respiratory cultures) was most common in public insurance compared to other insurance types. In multivariable logistic regression, public insurance was associated with greater use of recommended care relative to private insurance (OR = 1.16; 95% confidence interval: 1.10-1.22; P < .001), while being uninsured was associated with lower odds of using recommended care (OR = 0.37; 95% confidence interval: 0.31-0.46; P < .001).
For adults with CF in the United States, public insurance was associated with greater use of routine care than private coverage. Being uninsured was strongly associated with not using routine care. Further efforts to improve access to CF care should address the feasibility of universal and continuous insurance coverage in the CF population.
社会经济地位较低与囊性纤维化(CF)患者的不良预后相关。保险状况是否会影响该人群对治疗的依从性尚不清楚。
将囊性纤维化基金会患者登记处(2005 - 2013年)中年龄≥18岁的患者,根据报告的年度保险情况分为私人保险、公共保险(医疗补助、医疗保险或州医疗救助计划)、其他保险或无保险。随机效应逻辑回归评估保险状况变化与推荐常规治疗年度使用情况之间的关联。
共有18358名患者为分析贡献了94690人年的数据。在描述性分析中,与其他保险类型相比,公共保险患者对推荐常规治疗(每年≥4次门诊就诊、≥4次呼吸道培养和≥2次肺功能测试)以及对中重度肺部疾病患者推荐的慢性药物(若呼吸道培养中有铜绿假单胞菌,则使用多黏菌素B雾化吸入剂和吸入用妥布霉素或氨曲南)的依从性最为常见。在多变量逻辑回归中,相对于私人保险,公共保险与更多地使用推荐治疗相关(比值比[OR]=1.16;95%置信区间:1.10 - 1.22;P<.001),而未参保与使用推荐治疗的几率较低相关(OR=0.37;95%置信区间:0.31 - 0.46;P<.001)。
在美国,对于成年CF患者,公共保险与比私人保险更多地使用常规治疗相关。未参保与不使用常规治疗密切相关。改善CF治疗可及性的进一步努力应解决CF人群中普遍且持续的保险覆盖的可行性问题。