ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.
Barcelonaβeta Brain Research Center - Pasqual Maragall Foundation, Barcelona, Spain; CIBER Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain.
Environ Res. 2018 Apr;162:231-239. doi: 10.1016/j.envres.2018.01.012. Epub 2018 Jan 19.
Although exposure to natural outdoor environments has been consistently associated with improved perceived general health, available evidence on a protective association between this exposure and specific mental health disorders such as depression and anxiety is still limited.
The aim of this study was to evaluate the effects of long-term exposure to residential green and blue spaces on anxiety and depression and intake of related medication. Additionally, we aimed to explore potential mediators and effect modifiers of this association.
The study was based on an existing adult cohort (ALFA - Alzheimer and Families) and includes 958 adult participants from Barcelona recruited in 2013-2014. For each participant residential green and blue exposure indicators [surrounding greenness (NDVI), amount of green (land-cover) and access to major green spaces and blue spaces] were generated for different buffers (100m, 300m and 500m). Participants reported their history of doctor-diagnosed anxiety and depressive disorders and intake of related medication. Logistic regression models were applied to assess the corresponding associations.
Increasing surrounding greenness was associated with reduced odds of self-reported history of benzodiazepines [e.g. Odds ratio - OR (95%CI) = 0.62 (0.43, 0.89) for 1-interquartile range (IQR) increase in NDVI in a 300m buffer] and access to major green spaces was associated with self-reported history of depression [OR (95%CI) = 0.18 (0.06, 0.58)]. No statistically significant associations were observed with blue spaces. Air pollution (between 0.8% and 29.6%) and noise (between 2.2% and 5.3%) mediated a proportion of the associations observed, whereas physical activity and social support played a minor role.
Our findings suggest a potential protective role of green spaces on mental health (depression and anxiety) in adults, but further studies, especially longitudinal studies, are needed to provide further evidence of these benefits and of the mediation role of exposures like air pollution and noise.
尽管接触自然户外环境与改善整体健康感知有关,但关于这种接触与特定心理健康障碍(如抑郁和焦虑)之间存在保护关联的现有证据仍然有限。
本研究旨在评估长期暴露于住宅绿色和蓝色空间对焦虑和抑郁以及相关药物摄入的影响。此外,我们旨在探索这种关联的潜在中介和调节因素。
该研究基于现有的成人队列(ALFA-阿尔茨海默病和家庭),包括 2013 年至 2014 年在巴塞罗那招募的 958 名成年参与者。对于每个参与者,为不同缓冲区(100m、300m 和 500m)生成了住宅绿色和蓝色暴露指标(周围绿化度(NDVI)、绿色面积(土地覆盖)和通往主要绿色空间和蓝色空间的可达性)。参与者报告了他们被诊断患有焦虑和抑郁障碍的病史以及相关药物的摄入情况。应用逻辑回归模型评估相应的关联。
周围绿化度的增加与报告的苯二氮䓬类药物使用史减少有关[例如,在 300m 缓冲区中,NDVI 增加 1 个四分位距(IQR),则报告的苯二氮䓬类药物使用史的优势比(OR)(95%CI)为 0.62(0.43,0.89)],而主要绿色空间的可达性与抑郁史有关[OR(95%CI)=0.18(0.06,0.58)]。与蓝色空间没有观察到统计学上显著的关联。空气污染(在 0.8%至 29.6%之间)和噪声(在 2.2%至 5.3%之间)在一定程度上调节了所观察到的关联,而身体活动和社会支持则起到了次要作用。
我们的研究结果表明,绿色空间可能对成年人的心理健康(抑郁和焦虑)有保护作用,但需要进一步的研究,特别是纵向研究,以提供这些益处的进一步证据,以及空气污染和噪声等暴露的中介作用。