Bryskier A, Chantot J F, Veyssier P
Presse Med. 1985 Dec 21;14(45):2291-4.
Fluoroquinolones are new synthetic derivatives with a broad spectrum and a potent antibacterial activity this permits to assimilate these molecules as antibiotics. These compounds are characterized by a quinoline or a naphthyridine nucleus with a fluorine atom in position 6 and a piperazine or a pyrrole nucleus in position 7. The combination of their antibacterial properties and the good absorption and tissue distribution allows their use in the treatment of the main infections caused by sensitive strains. The clinical and biological tolerance of these drugs are usually excellent.
氟喹诺酮类是新型合成衍生物，具有广谱和强效抗菌活性，这使得这些分子可被视为抗生素。这些化合物的特征在于6位带有氟原子的喹啉或萘啶核以及7位的哌嗪或吡咯核。它们抗菌特性与良好的吸收及组织分布相结合，使其可用于治疗由敏感菌株引起的主要感染。这些药物的临床和生物学耐受性通常极佳。
