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印度卡纳塔克邦赖朱尔县接受抗逆转录病毒治疗的人类免疫缺陷病毒阳性患者中牙周炎和软组织病变的患病率

Prevalence of Periodontitis and Soft Tissue Lesions among Human Immunodeficiency Virus-positive Patients on Antiretroviral Therapy in Raichur Taluk, Karnataka, India.

作者信息

Muralidharan Shrikanth, Acharya Arun Kumar, Margabandhu Shanthi, Kalekhan Sufiyan, Ahsan Sameer, Kulkarni Dinraj

机构信息

Department of Public Health Dentistry, M. A. Rangoonwala College of Dental Sciences & Research Centre, Pune, Maharashtra, India, India, Phone: +918308008831, e-mail:

Department of Public Health Dentistry, Navodaya Dental College & Hospital, Raichur, Karnataka, India.

出版信息

J Contemp Dent Pract. 2018 Jan 1;19(1):42-46. doi: 10.5005/jp-journals-10024-2209.

Abstract

INTRODUCTION

In countries where human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) is widespread and highly active antiretroviral therapy (HAART) medications are too expensive, or patients are failing HAART, oral disease management and risk remain an important issue.

AIM

The aim of the study was to evaluate the prevalence of oral mucosal lesions and periodontitis among the HIV-positive adult patients and assess the association of these lesions with age, sex, duration of HIV, time on ART, dietary habits, and oral hygiene habits.

MATERIALS AND METHODS

Sample size was 170. Demographic data of the patients along with community periodontal index (CPI) and loss of attachment (LA) were recorded. Oral soft tissue lesions, such as ulcerations, sores, erosions, and fissures were also recorded. The study was carried out in Raichur Taluk, Karnataka, India. Convenience sampling design was followed. Statistical Package for the Social Sciences (SPSS) version 20.0 (Chicago, USA) was used for data analysis. Chi-square test was carried out; p < 0.05 was considered to be statistically significant.

RESULTS

There was no association between the oral mucosal conditions and the age and the adverse habits, such as tobacco and alcohol, CD4 count, and the time duration of HIV and ART among these patients. A higher percentage of people with 4 to 5 mm of pockets was seen with those who cleaned their teeth with a finger, which was statistically significant.

CLINICAL SIGNIFICANCE

The present study highlights the poor condition of the oral health of these patients and their unmet dental needs.

摘要

引言

在人类免疫缺陷病毒/获得性免疫缺陷综合征(HIV/AIDS)广泛流行且高效抗逆转录病毒治疗(HAART)药物过于昂贵,或患者HAART治疗失败的国家,口腔疾病管理和风险仍然是一个重要问题。

目的

本研究的目的是评估HIV阳性成年患者口腔黏膜病变和牙周炎的患病率,并评估这些病变与年龄、性别、HIV病程、接受抗逆转录病毒治疗的时间、饮食习惯和口腔卫生习惯之间的关联。

材料与方法

样本量为170。记录患者的人口统计学数据以及社区牙周指数(CPI)和附着丧失(LA)情况。还记录了口腔软组织病变,如溃疡、口疮、糜烂和裂隙。该研究在印度卡纳塔克邦赖丘尔县进行。采用方便抽样设计。使用社会科学统计软件包(SPSS)20.0版(美国芝加哥)进行数据分析。进行卡方检验;p<0.05被认为具有统计学意义。

结果

在这些患者中,口腔黏膜状况与年龄、不良习惯(如吸烟和饮酒)、CD4细胞计数、HIV病程和抗逆转录病毒治疗时间之间没有关联。用手指刷牙的人群中,牙周袋深度为4至5毫米的比例更高,这具有统计学意义。

临床意义

本研究突出了这些患者口腔健康状况不佳以及他们未满足的牙科需求。

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