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在本地治里一所选定的三级护理医院接受抗逆转录病毒治疗的艾滋病毒感染者中口腔病变的患病率及其相关危险因素——一项横断面分析研究

Prevalence of Oral Lesions and Its Associated Risk Factors Among PLHIV Availing Anti-Retroviral Therapy from a Selected Tertiary Care Hospital, Puducherry - A Cross Sectional Analytical Study.

作者信息

Jana Pradip Kumar, Sahu Swaroop Kumar, Sivaranjini K, Hamide Abdoul, Roy Gautam

机构信息

Department of Preventive and Social Medicine, JIPMER, Puducherry, India.

出版信息

Indian J Community Med. 2022 Apr-Jun;47(2):235-239. doi: 10.4103/ijcm.ijcm_850_21. Epub 2022 Jul 11.

Abstract

BACKGROUND AND OBJECTIVES

Oral lesions are among the earliest and most important indicators of infection with human immunodeficiency virus (HIV). The presence of oral lesions has a significant impact on the physical and mental health of the PLHIV. Hence, a novel attempt is made to assess the prevalence of various types of oral lesions among the adult people living with human immunodeficiency virus (PLHIV) undergoing antiretroviral therapy.

METHODOLOGY

In this facility-based cross-sectional study, a total of 239 out of 300 eligible PLHIV were assessed between September and October 2018. All consecutive eligible patients encountered during the data collection period were included. Oral examination was carried out using disposable mouth mirrors, sterile piece of cotton, and bright illuminated torch.

RESULTS

The prevalence of oral mucosal abnormalities was found to be 25% (95% confidence interval: 20.03-30.97). The most prevalent oral lesions were acute necrotizing ulcerative gingivitis, acute necrotizing ulcerative periodontitis, and candidiasis. CD4 count <200 cells/mm, current tobacco use, and alcohol usage were significantly associated with the prevalence of oral lesions.

CONCLUSION AND RECOMMENDATIONS

The study revealed that one-fourth of the study participants had oral lesions. Strategies for early detection and prompt treatment of oral lesions need to be planned and incorporated in the program to reduce the morbidity due to oral lesions.

摘要

背景与目的

口腔病变是人类免疫缺陷病毒(HIV)感染最早且最重要的指标之一。口腔病变的存在对艾滋病毒感染者的身心健康有重大影响。因此,我们进行了一项新的尝试,以评估接受抗逆转录病毒治疗的成年艾滋病毒感染者中各种口腔病变的患病率。

方法

在这项基于机构的横断面研究中,2018年9月至10月期间,对300名符合条件的艾滋病毒感染者中的239人进行了评估。纳入了数据收集期间遇到的所有连续符合条件的患者。使用一次性口镜、无菌棉球和明亮的照明手电筒进行口腔检查。

结果

发现口腔黏膜异常的患病率为25%(95%置信区间:20.03 - 30.97)。最常见的口腔病变是急性坏死性溃疡性牙龈炎、急性坏死性溃疡性牙周炎和念珠菌病。CD4细胞计数<200个/mm、当前吸烟和饮酒与口腔病变的患病率显著相关。

结论与建议

该研究表明,四分之一的研究参与者有口腔病变。需要制定并将口腔病变的早期检测和及时治疗策略纳入项目中,以降低口腔病变导致的发病率。

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