爱泼斯坦-巴尔病毒与噬血细胞性淋巴组织细胞增生症
Epstein-Barr Virus and Hemophagocytic Lymphohistiocytosis.
作者信息
Marsh Rebecca A
机构信息
Division of Bone Marrow Transplantation and Immune Deficiency, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.
出版信息
Front Immunol. 2018 Jan 8;8:1902. doi: 10.3389/fimmu.2017.01902. eCollection 2017.
Epstein-Barr virus (EBV) is a ubiquitous virus that infects nearly all people worldwide without serious sequela. However, for patients who have genetic diseases which predispose them to the development of hemophagocytic lymphohistiocytosis (HLH), EBV infection is a life-threatening problem. As a part of a themed collection of articles on EBV infection and human primary immune deficiencies, we will review key concepts related to the understanding and treatment of HLH.
爱泼斯坦-巴尔病毒（EBV）是一种普遍存在的病毒，几乎感染了全世界所有的人，且不会产生严重的后遗症。然而，对于那些患有遗传性疾病且易发展为噬血细胞性淋巴组织细胞增生症（HLH）的患者来说，EBV感染是一个危及生命的问题。作为关于EBV感染与人类原发性免疫缺陷的主题文章集的一部分，我们将回顾与HLH的理解和治疗相关的关键概念。
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