Bruetman Julio E, Montes Onganía Agustín, Finn Bárbara C, Young Pablo
Servicio de Clínica Médica, Hospital Británico de Buenos Aires, Argentina.
Servicio de Clínica Médica, Hospital Británico de Buenos Aires, Argentina. E-mail:
Medicina (B Aires). 2018;78(1):41-43.
Angioedema induced by angiotensin converting enzyme inhibitors is a rare entity characterized by skin and mucosal edema, due to increased vascular permeability caused by inhibition of the converting enzyme and subsequent increase in bradykinin. It frequently presents with facial and mucosal involvement, being uncommon the intestinal or airway compromise. Intestinal angioedema may be associated with facial or isolated angioedema, the latter being exceptional. It is associated with recurrent episodes of pain, abdominal distention and watery diarrhea which complete recovery in two or three days. Although it is a rare entity, the fact that it is associated with frequently used drugs makes us include it in the differential diagnosis of recurrent abdominal pain. We report a case of isolated intestinal angioedema associated with the use of enalapril.
血管紧张素转换酶抑制剂所致血管性水肿是一种罕见病症，其特征为皮肤和黏膜水肿，这是由于转换酶受抑制导致血管通透性增加以及随后缓激肽增多所致。它常表现为面部和黏膜受累，肠道或气道受累情况不常见。肠道血管性水肿可能与面部血管性水肿相关或单独出现，后者极为罕见。它与反复出现的疼痛、腹胀和水样腹泻有关，通常在两三天内完全恢复。尽管这是一种罕见病症，但因其与常用药物相关，我们在复发性腹痛的鉴别诊断中应考虑到它。我们报告一例与使用依那普利相关的孤立性肠道血管性水肿病例。
