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终生物质使用与近期情绪障碍诊断之间的独立关联以及家庭粮食不安全对其的效应修正。

Independent associations and effect modification between lifetime substance use and recent mood disorder diagnosis with household food insecurity.

作者信息

Davison Karen M, Holloway Cliff, Gondara Lovedeep, Hatcher Anne S

机构信息

School of Nursing, University of British Columbia, Vancouver, British Columbia, Canada.

Health Science Program, Department of Biology, Kwantlen Polytechnic University, Surrey, British Columbia, Canada.

出版信息

PLoS One. 2018 Jan 23;13(1):e0191072. doi: 10.1371/journal.pone.0191072. eCollection 2018.

Abstract

Poor mental health and substance use are associated with food insecurity, however, their potential combined effects have not been studied. This study explored independent associations and effect modification between lifetime substance use and mood disorder in relation to food insecurity. Poisson regression analysis of data from British Columbia respondents (n = 13,450; 12 years+) in the 2007/08 Canadian Community Health Survey was conducted. Measures included The Household Food Security Survey Module (7.3% food insecure), recent diagnosis of a mood disorder (self-reported; 9.5%), lifetime use of cannabis, cocaine/crack, ecstasy, hallucinogens, and speed, any lifetime substance use, sociodemographic covariates, and the interaction terms of mood disorder by substance. For those with recent diagnosis of a mood disorder the prevalence of lifetime substance use ranged between 1.2 to 5.7% and were significantly higher than those without recent mood disorder diagnosis or lifetime use of substances (p's < 0.05). For respondents with a recent mood disorder diagnosis or who used cannabis, food insecurity prevalence was higher compared to the general sample (p < 0.001); prevalence was lower for cocaine/crack use (p < 0.05). Significant effect modification was found between mood disorder with cannabis, ecstasy, hallucinogen and any substance use over the lifetime (PRs 0.51 to 0.64, p's 0.022 to 0.001). Independent associations were found for cocaine/crack and speed use (PRs 1.68, p's < 0.001) and mood disorder (PRs 2.02, p's < 0.001). Based on these findings and the existing literature, future study about coping and resilience in the context of substance use, mental health, and food insecurity may lead to the development of relevant interventions aimed at mental well-being and food security.

摘要

心理健康状况不佳和物质使用与粮食不安全有关,然而,它们潜在的综合影响尚未得到研究。本研究探讨了终生物质使用与情绪障碍之间与粮食不安全相关的独立关联和效应修正。对2007/08年加拿大社区健康调查中不列颠哥伦比亚省受访者(n = 13450;12岁及以上)的数据进行了泊松回归分析。测量指标包括家庭粮食安全调查模块(7.3%粮食不安全)、近期情绪障碍诊断(自我报告;9.5%)、终生使用大麻、可卡因/快克、摇头丸、致幻剂和安非他明、任何终生物质使用、社会人口统计学协变量以及情绪障碍与物质的交互项。对于近期诊断为情绪障碍的人,终生物质使用的患病率在1.2%至5.7%之间,显著高于没有近期情绪障碍诊断或终生未使用物质的人(p值<0.05)。对于近期诊断为情绪障碍或使用大麻的受访者,与总体样本相比,粮食不安全患病率更高(p < 0.001);可卡因/快克使用的患病率较低(p < 0.05)。在情绪障碍与大麻、摇头丸、致幻剂以及任何终生物质使用之间发现了显著的效应修正(PRs为0.51至0.64,p值为0.022至0.001)。发现可卡因/快克和安非他明使用(PRs为1.68,p值<0.001)以及情绪障碍(PRs为2.02,p值<0.001)存在独立关联。基于这些发现和现有文献,未来关于物质使用、心理健康和粮食不安全背景下应对和恢复力的研究可能会导致开发旨在促进心理健康和粮食安全的相关干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1522/5779657/f6e733f7a24d/pone.0191072.g001.jpg

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