临床疑似内脏型弓首蛔虫病患者中弓首蛔虫病的发病率：斯里兰卡的一项回顾性描述性研究

Frequency of Toxocariasis among Patients Clinically Suspected to Have Visceral Toxocariasis: A Retrospective Descriptive Study in Sri Lanka.

作者信息

Iddawela Devika, Ehambaram Kiruthiha, Atapattu Dhilma, Pethiyagoda Kalyani, Bandara Lakmalee

机构信息

Department of Parasitology, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.

Department of Community Medicine, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.

出版信息

J Parasitol Res. 2017;2017:4368659. doi: 10.1155/2017/4368659. Epub 2017 Dec 6.

DOI:10.1155/2017/4368659

PMID:29362672

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5736924/

Abstract

INTRODUCTION

Human toxocariasis is caused by several species of the nematode . Two common clinical syndromes are ocular and visceral larva migrans.

OBJECTIVES

To determine the antibody positivity in clinically suspected VLM patients and to describe demographic factors and clinical manifestations of seropositive patients.

METHODS

522 clinically suspected patients were studied between 1993 and 2014. Relevant data was gathered from referral letters. Serum samples were subjected to .

RESULTS

Overall, seropositivity was 50.2% (262), of which 109 (40.8%) were positive at high level of antibody carriage and 153 (58.4%) were positive at low levels. The seropositives ranged from 3 months to 70 years (mean = 7.8). Younger age group had higher levels of seropositivity and it was statistically significant. Majority of children under 5 years were seropositive (47.7%, = 125). Seropositivity was common in males (55.3%, = 145). Clinical manifestations of seropositives include lymphadenopathy (24.1%) skin rash (22.5%), dyspnoea (21.7%), fever (21%), hepatosplenomegaly (9.2%), and abdominal pain (3.8%). 197 (75.2%) seropositive cases had eosinophilia. These symptoms were not statistically significant.

CONCLUSIONS

This study confirms toxocariasis as an important cause of childhood ill health identifying common clinical symptoms recommending preventive measures to limit transmission.

摘要

引言

人体弓蛔虫病由几种线虫引起。两种常见的临床综合征是眼部幼虫移行症和内脏幼虫移行症。

目的

确定临床疑似内脏幼虫移行症患者的抗体阳性率，并描述血清阳性患者的人口统计学因素和临床表现。

方法

1993年至2014年期间对522例临床疑似患者进行了研究。从转诊信中收集相关数据。对血清样本进行了……

结果

总体而言，血清阳性率为50.2%（262例），其中109例（40.8%）抗体携带水平高呈阳性，153例（58.4%）抗体水平低呈阳性。血清阳性者年龄范围为3个月至70岁（平均=7.8岁）。较年轻年龄组血清阳性率较高，且具有统计学意义。5岁以下儿童大多数血清呈阳性（47.7%，n=125）。血清阳性在男性中常见（55.3%，n=145）。血清阳性者的临床表现包括淋巴结病（24.1%）、皮疹（22.5%）、呼吸困难（21.7%）、发热（21%）、肝脾肿大（9.2%）和腹痛（3.8%）。197例（75.2%）血清阳性病例有嗜酸性粒细胞增多。这些症状无统计学意义。