Department of Medical Microbiology, Hitit University School of Medicine, Corum, Turkey; Department of Medical Microbiology and Clinical Microbiology, Near East University School of Medicine, Nicosia, Cyprus.
Adv Parasitol. 2020;109:465-482. doi: 10.1016/bs.apar.2020.01.021. Epub 2020 Feb 10.
Toxocariasis in humans is considered a rare disease in Turkey, and the absence of specific symptoms of this disease is probably the main reason for clinicians to underestimate and underdiagnose the disease. Although there are several seroepidemiological studies on visceral larva migrans in the country, a comparison between them is difficult as the serological tests are not standardised. After the introduction of the easily accessible ELISA kit in the market, the number of seroepidemiological studies has increased in which the reported rates ranged between 1% and 56%. Similar to other countries, Toxocara seropositivity in Turkey is more common in men, childhood, in those living in rural area, having a low income level, owning dogs, and biting their nails or practicing geophagia. In addition, toxocariasis is a risk factor for veterinarians, farmers, and pet-shop workers. Toxocara seroprevalence is significantly higher in respiratory, neuropsychiatric, musculoskeletal, skin and abdominal disorders. There are also many studies showing the importance of eosinophilia in toxocariasis. In conclusion, although there are many studies on toxocariasis in Turkey, it is still not well understood to what extent the infection is responsible for a plethora ascribed symptoms. Standardisation of the diagnostic methods and the use of molecular techniques could further throw light in the real epidemiology and the role played by the infection to induce signs and symptoms.
在土耳其,人类弓蛔虫病被认为是一种罕见疾病,而这种疾病缺乏特异性症状,这可能是临床医生低估和漏诊该疾病的主要原因。尽管该国已经进行了几项关于内脏幼虫移行症的血清流行病学研究,但由于血清学检测方法不标准化,很难对它们进行比较。在市场上推出易于获取的 ELISA 试剂盒后,血清流行病学研究的数量有所增加,报告的发病率在 1%至 56%之间。与其他国家一样,土耳其的弓蛔虫血清阳性率在男性、儿童、农村地区居民、收入水平较低、养狗、咬指甲或食土的人群中更为常见。此外,弓蛔虫病也是兽医、农民和宠物店工作人员的一个危险因素。弓蛔虫病血清阳性率在呼吸道、神经精神、肌肉骨骼、皮肤和腹部疾病中显著更高。还有许多研究表明嗜酸粒细胞增多症在弓蛔虫病中的重要性。总之,尽管土耳其已经进行了许多关于弓蛔虫病的研究,但对于感染在多大程度上导致了大量归因于感染的症状,仍缺乏了解。诊断方法的标准化和分子技术的应用可以进一步阐明实际的流行病学和感染所起的作用。