Estlander T, Jolanki R, Kanerva L
Contact Dermatitis. 1986 Jan;14(1):49-52. doi: 10.1111/j.1600-0536.1986.tb01152.x.
4 workers developed hand dermatitis in an automated starch modification process plant. 2,3-epoxypropyl trimethyl ammonium chloride (EPTMAC), a quaternary ammonium compound used as a cationizing chemical, produced allergic reactions in all 4 patients. They had only been in contact with EPTMAC for a short time before developing dermatitis, which indicates that EPTMAC is a strong sensitizer. Immunohistochemistry and electron microscopy showed the features of an allergic patch test. An industrial hygiene project was initiated at the factory to prevent new cases. It revealed many risks of skin contact with the process chemicals. Thus an automated process does not guarantee protection.
在一家自动化淀粉改性加工厂中，有4名工人患上了手部皮炎。2,3-环氧丙基三甲基氯化铵（EPTMAC）是一种用作阳离子化化学品的季铵化合物，在所有4名患者中均引发了过敏反应。他们在患皮炎之前仅短时间接触过EPTMAC，这表明EPTMAC是一种强致敏剂。免疫组织化学和电子显微镜检查显示出过敏斑贴试验的特征。工厂启动了一项工业卫生项目以预防新病例的出现。该项目揭示了皮肤接触加工化学品的诸多风险。因此，自动化工艺并不能保证防护效果。
