Stroke. 2018 Mar;49(3):e123-e128. doi: 10.1161/STR.0000000000000159. Epub 2018 Jan 24.
Dysphagia screening protocols have been recommended to identify patients at risk for aspiration. The American Heart Association convened an evidence review committee to systematically review evidence for the effectiveness of dysphagia screening protocols to reduce the risk of pneumonia, death, or dependency after stroke.
The Medline, Embase, and Cochrane databases were searched on November 1, 2016, to identify randomized controlled trials (RCTs) comparing dysphagia screening protocols or quality interventions with increased dysphagia screening rates and reporting outcomes of pneumonia, death, or dependency.
Three RCTs were identified. One RCT found that a combined nursing quality improvement intervention targeting fever and glucose management and dysphagia screening reduced death and dependency but without reducing the pneumonia rate. Another RCT failed to find evidence that pneumonia rates were reduced by adding the cough reflex to routine dysphagia screening. A smaller RCT randomly assigned 2 hospital wards to a stroke care pathway including dysphagia screening or regular care and found that patients on the stroke care pathway were less likely to require intubation and mechanical ventilation; however, the study was small and at risk for bias.
There were insufficient RCT data to determine the effect of dysphagia screening protocols on reducing the rates of pneumonia, death, or dependency after stroke. Additional trials are needed to compare the validity, feasibility, and clinical effectiveness of different screening methods for dysphagia.
吞咽障碍筛查方案已被推荐用于识别有发生吸入风险的患者。美国心脏协会召集了一个证据审查委员会,系统地审查了吞咽障碍筛查方案在降低卒中后肺炎、死亡或依赖风险方面的有效性证据。
于 2016 年 11 月 1 日检索了 Medline、Embase 和 Cochrane 数据库,以确定比较吞咽障碍筛查方案或质量干预措施与增加吞咽障碍筛查率以及报告肺炎、死亡或依赖结果的随机对照试验(RCT)。
确定了三项 RCT。一项 RCT 发现,针对发热和血糖管理以及吞咽障碍筛查的联合护理质量改进干预措施可降低死亡和依赖率,但并未降低肺炎发生率。另一项 RCT 未能发现通过将咳嗽反射添加到常规吞咽障碍筛查中可降低肺炎发生率的证据。一项较小的 RCT 将 2 个医院病房随机分配到包括吞咽障碍筛查或常规护理的卒中护理路径中,发现接受卒中护理路径的患者更不可能需要插管和机械通气;然而,该研究规模较小,存在偏倚风险。
没有足够的 RCT 数据来确定吞咽障碍筛查方案在降低卒中后肺炎、死亡或依赖发生率方面的效果。需要进一步的试验来比较不同吞咽障碍筛查方法的有效性、可行性和临床效果。