联合药物化疗与大块同种异体骨移植治疗股骨包虫病
Combination drug chemotherapy and massive skeletal allograft in the management of hydatid disease of femur.
作者信息
Gautam Deepak, Malhotra Rajesh, Dubey Siddharth
机构信息
Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, Delhi, India.
出版信息
BMJ Case Rep. 2018 Jan 23;2018:bcr-2017-223332. doi: 10.1136/bcr-2017-223332.
Abstract
Hydatid disease of long bone is a rare presentation. Chemotherapy and surgery constitute the standard treatment of choice. Non-union of a pathological fracture of femur particularly due to hydatid disease has been known to be resistant to treatment. These resistant cases require combination drug chemotherapy and excision of the lesion. Reconstruction of a large skeletal defect following resection of the lesion poses a challenge to the orthopaedic surgeons. We discuss the staged treatment of hydatid disease of shaft of femur with resection and cement spacer application followed by reconstruction using massive skeletal allograft under cover of combination drug chemotherapy.
摘要
长骨包虫病是一种罕见的病症。化疗和手术是标准的首选治疗方法。已知股骨病理性骨折尤其是由包虫病引起的骨折不愈合对治疗具有抗性。这些抗性病例需要联合药物化疗和病灶切除。病灶切除后大的骨骼缺损的重建对骨科医生构成了挑战。我们讨论了股骨干包虫病的分期治疗，包括切除和应用骨水泥间隔物，随后在联合药物化疗的掩护下使用大块骨骼同种异体骨进行重建。
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