DePaola L G, Peterson D E, Overholser C D, Suzuki J B, Minah G E, Williams L T, Stansbury D M, Niehaus C S
J Am Dent Assoc. 1986 Feb;112(2):198-203.
Common oral complications of chemotherapy include mucositis, infections secondary to profound bone marrow aplasia, and gingival bleeding. Mucositis and infections were treated with appropriate antibiotic therapy; a symptomatic tooth was extracted before chemotherapy was begun. Transfusions were performed to obtain adequate platelet levels. A regimen of ticarcillin disodium and gentamicin sulfate is recommended for antibiotic prophylaxis for selected dental procedures.
化疗常见的口腔并发症包括黏膜炎、严重骨髓再生障碍继发的感染以及牙龈出血。黏膜炎和感染采用适当的抗生素治疗;在开始化疗前拔除有症状的牙齿。进行输血以维持足够的血小板水平。对于特定的牙科手术,推荐使用替卡西林钠和硫酸庆大霉素进行抗生素预防。