Alušík Tomáš, Alušík Štefan
Cas Lek Cesk. 2017 Winter;156(8):454-457.
The authors describe the history of treatment of gout by using colchicine (colchicum; the active substance of Colchicum autumnale). The references to this plant and its effects (incl. several recipes for the preparation of remedies) in the gout treatment date back already from the antiquity, but the indisputable evidence of its use in the therapy of the disease in question comes only from the 6th century AD, by Alexander of Tralles. At present, colchicine became an officially preferred drug. Some other examples of medicines of plant origin (e.g. verbena), which were used already by ancient civilizations and are often chosen for therapy even today. The potential of medicinal drugs hasnt been completely exhausted yet.
作者描述了使用秋水仙碱(秋水仙;秋水仙的活性物质)治疗痛风的历史。在痛风治疗中提及这种植物及其作用(包括几种制备药物的配方)可追溯到古代,但关于其在该疾病治疗中使用的确凿证据直到公元6世纪才由特拉勒斯的亚历山大提供。目前,秋水仙碱已成为官方首选药物。其他一些植物源药物的例子(如马鞭草),古代文明就已使用,甚至如今仍常被选作治疗药物。药用植物的潜力尚未完全耗尽。