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[传统医学与当下:痛风的治疗]

[Traditional medicine and the present: the therapy of gout].

作者信息

Alušík Tomáš, Alušík Štefan

出版信息

Cas Lek Cesk. 2017 Winter;156(8):454-457.

PMID:29368528
Abstract

The authors describe the history of treatment of gout by using colchicine (colchicum; the active substance of Colchicum autumnale). The references to this plant and its effects (incl. several recipes for the preparation of remedies) in the gout treatment date back already from the antiquity, but the indisputable evidence of its use in the therapy of the disease in question comes only from the 6th century AD, by Alexander of Tralles. At present, colchicine became an officially preferred drug. Some other examples of medicines of plant origin (e.g. verbena), which were used already by ancient civilizations and are often chosen for therapy even today. The potential of medicinal drugs hasnt been completely exhausted yet.

摘要

作者描述了使用秋水仙碱(秋水仙;秋水仙的活性物质)治疗痛风的历史。在痛风治疗中提及这种植物及其作用(包括几种制备药物的配方)可追溯到古代,但关于其在该疾病治疗中使用的确凿证据直到公元6世纪才由特拉勒斯的亚历山大提供。目前,秋水仙碱已成为官方首选药物。其他一些植物源药物的例子(如马鞭草),古代文明就已使用,甚至如今仍常被选作治疗药物。药用植物的潜力尚未完全耗尽。

相似文献

1
[Traditional medicine and the present: the therapy of gout].[传统医学与当下:痛风的治疗]
Cas Lek Cesk. 2017 Winter;156(8):454-457.
2
From poison to drug: new recipes discovered containing colchicine as a remedy for Podagra in Rome and Byzantium.从毒药到药物:在罗马和拜占庭发现了含有秋水仙素的新配方,作为痛风的治疗方法。
Clin Exp Rheumatol. 2019 Jul-Aug;37(4):540-545. Epub 2018 Nov 19.
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Colchicum Genus in the Writings of Ancient Greek and Byzantine Physicians.古希腊和拜占庭医师文献中的秋水仙属
Curr Pharm Des. 2018;24(6):648-653. doi: 10.2174/1381612824666180115111546.
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Isolating Colchicine in 19th Century: An Old Drug Revisited.19 世纪的秋水仙素提取:一种被重新审视的老药。
Curr Pharm Des. 2018;24(6):654-658. doi: 10.2174/1381612824666180115105850.
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Colchicine: A Review on Chemical Structure and Clinical Usage.秋水仙碱:化学结构与临床应用综述
Infect Disord Drug Targets. 2018;18(2):105-121. doi: 10.2174/1871526517666171017114901.
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Colchicine in Gout: An Update.秋水仙碱治疗痛风:最新进展。
Curr Pharm Des. 2018;24(6):684-689. doi: 10.2174/1381612824999180115103951.
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Effects of colchicine on risk of cardiovascular events among patients with gout: as evidence accrues, is it time for a randomised trial?秋水仙碱对痛风患者心血管事件风险的影响:随着证据的积累,是否到了进行随机试验的时候?
Ann Rheum Dis. 2016 May;75(5):e28. doi: 10.1136/annrheumdis-2016-209294. Epub 2016 Feb 18.
8
The complete chloroplast genome of colchicine plants (Colchicum autumnale L. and Gloriosa superba L.) and its application for identifying the genus.秋水仙碱植物(秋水仙Colchicum autumnale L.和嘉兰Gloriosa superba L.)的完整叶绿体基因组及其在属鉴定中的应用
Planta. 2015 Jul;242(1):223-37. doi: 10.1007/s00425-015-2303-7. Epub 2015 Apr 23.
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Update on colchicine, 2017.2017 年秋水仙碱研究进展。
Rheumatology (Oxford). 2018 Jan 1;57(suppl_1):i4-i11. doi: 10.1093/rheumatology/kex453.
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Colchicine: New Insights to an Old Drug.秋水仙碱:对一种老药的新认识。
Am J Ther. 2015 Sep-Oct;22(5):e151-7. doi: 10.1097/01.mjt.0000433937.07244.e1.

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