Vitiello Paola, Taramasso Lucia, Ricci Elena, Maggi Paolo, Martinelli Canio, Gabrielli Chiara, Vittorio De Socio Giuseppe, Di Cristo Valentina, Rusconi Stefano, Falasca Katia, Menzaghi Barbara, Tebini Alessandro, Di Biagio Antonio
a Infectious Diseases Unit , ASST Valle Olona, Busto Arsizio Hospital , Busto Arsizio , Italy.
b Infectious Diseases Clinic and University of Genova , Genova , Italy.
J Women Aging. 2019 Mar-Apr;31(2):176-188. doi: 10.1080/08952841.2018.1428100. Epub 2018 Jan 25.
This is a multicenter cross-sectional study where we aimed to detect the rate of osteopenia/osteoporosis in an HIV female population (WLWHIV) by means of "heel quantitative ultrasound" (QUS) measurement. We enrolled 273 patients, mean age 48.1 years, 36% menopausal, 96% on combination antiretroviral therapy (cART). Calcaneal measure of bone mass index by QUS revealed osteopenia and osteoporosis in 76 (27.8%) and 16 (5.9%) WLWHIV. Our data underline the correlation between low QUS parameters and traditional risk factors for osteoporosis rather than with cART exposure, thus suggesting the crucial importance of detection and correction of traditional risk factors for osteoporosis in WLWHIV.
这是一项多中心横断面研究，我们旨在通过“足跟定量超声”（QUS）测量来检测感染HIV的女性人群（感染HIV的女性）中的骨质减少/骨质疏松症发生率。我们纳入了273名患者，平均年龄48.1岁，36%为绝经后女性，96%接受联合抗逆转录病毒治疗（cART）。通过QUS测量跟骨骨量指数显示，76名（27.8%）感染HIV的女性存在骨质减少，16名（5.9%）存在骨质疏松。我们的数据强调了低QUS参数与骨质疏松传统危险因素之间的相关性，而非与cART暴露的相关性，从而表明在感染HIV的女性中检测和纠正骨质疏松传统危险因素至关重要。
