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使用跟骨定量超声对查谟城市女性进行骨质疏松症和骨质减少的初步筛查。

Preliminary screening of osteoporosis and osteopenia in urban women from Jammu using calcaneal QUS.

作者信息

Sharma Sudhaa, Tandon Vishal R, Mahajan Annil, Kour Avinash, Kumar Dinesh

机构信息

Department of Obstetrics and Gynaecology, Govt. Medical College, Jammu, J&K, India.

出版信息

Indian J Med Sci. 2006 May;60(5):183-9.

PMID:16733289
Abstract

BACKGROUND

Osteoporosis is a major public health problem, associated with substantial morbidity and socio-economic burden. An early detection can help in reducing the fracture rates and overall socio-economic burden in such patients.

AIM

The present study was carried out to screen the bone status (osteopenia and osteoporosis) above the age of 25 years in urban women population in this region.

MATERIALS AND METHODS

A hospital based study was carried out in 158 women by calculating T-scores utilizing calcaneal QUS as diagnostic tool.

RESULTS

The result suggested that a substantial female population had oesteopenia and osteoporosis after the age of 45 years. The incidence of osteoporosis was (20.25%) and osteopenia (36.79%) with maximum number of both osteoporosis and osteopenic women recorded in the age group of (55-64 years). After the age of 65 years, there was an almost 100% incidence of either osteopenia or osteoporosis, indicating that it increases with age and in postmenopausal period, thereby suggesting lack of estrogenic activity might be responsible for this increasing trend. Religion, caste and diet had an influence on the outcome of osteopenic and osteoporosis score in present study, but still it has to be substantiated by conducting larger randomized clinical trials in future.

CONCLUSION

A substantial female population was screened for osteoporosis and osteopenia using calcaneal QUS method utilizing same WHO T score criteria that otherwise shall remain undiagnosed and face the complications and menace of osteoporosis.

摘要

背景

骨质疏松症是一个重大的公共卫生问题,伴随着严重的发病率和社会经济负担。早期检测有助于降低此类患者的骨折率和总体社会经济负担。

目的

本研究旨在筛查该地区25岁以上城市女性人群的骨状况(骨质减少和骨质疏松症)。

材料与方法

以医院为基础,对158名女性进行研究,使用跟骨定量超声计算T值作为诊断工具。

结果

结果表明,45岁以后有相当一部分女性人群患有骨质减少和骨质疏松症。骨质疏松症的发病率为(20.25%),骨质减少的发病率为(36.79%),骨质疏松症和骨质减少女性人数最多的年龄组为(55 - 64岁)。65岁以后,骨质减少或骨质疏松症的发病率几乎达到100%,表明其随年龄增长以及绝经后而增加,从而提示雌激素活性缺乏可能是这种上升趋势的原因。在本研究中,宗教、种姓和饮食对骨质减少和骨质疏松症评分结果有影响,但仍需在未来通过开展更大规模的随机临床试验来证实。

结论

使用跟骨定量超声方法,按照世界卫生组织相同的T值标准,对相当一部分女性人群进行了骨质疏松症和骨质减少的筛查,否则她们将仍未被诊断出来,并面临骨质疏松症的并发症和威胁。

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