Burhop James, Gibson Jennifer, de Boer Justin, Heydarian Cyrus
From the Departments of Emergency Medicine and Pediatrics, Children's Hospital of the King's Daughters, Norfolk, VA.
Pediatr Emerg Care. 2020 Jan;36(1):e1-e3. doi: 10.1097/PEC.0000000000001412.
Scurvy in modern times may not be as rare as previously thought. The link between adequate intake of vitamin C and scurvy has been known since ancient times and is recorded in Ebers Papyrus. Recent reports indicate that, with restricted diets, vitamin C deficiency is being seen in infants exclusively fed plant-based formula and children with oral aversion, autism, restricted diets, and cerebral palsy. Additional at-risk groups include the older adults and patients having alcoholism. Often costly, emergency department visits and elaborate diagnostic studies lead to fruitless results when a simple diet history is often overlooked. Here, we report a case of pediatric scurvy in an 11-year-old autistic child with a restricted diet who presented with refusal to walk, fatigue, a purpuric rash, and gingival bleeding. The diagnosis was made based on diet history, physical examination findings, and symptom resolution with vitamin C supplementation. Our case report reaffirms that vitamin C deficiency still occurs and should be considered in children with restrictive diets. Early recognition of this disease by physicians provides early diagnosis, avoids costly diagnostic workup and hospitalization, and expedites effective treatment.
现代坏血病可能并不像以前认为的那么罕见。充足摄入维生素C与坏血病之间的联系自古以来就为人所知,并记载于《埃伯斯纸草书》中。最近的报告表明,由于饮食受限,纯植物性配方奶粉喂养的婴儿以及有口腔厌恶、自闭症、饮食受限和脑瘫的儿童中出现了维生素C缺乏症。其他高危人群包括老年人和酗酒患者。当简单的饮食史常常被忽视时,急诊科就诊和复杂的诊断研究往往代价高昂且结果徒劳。在此,我们报告一例11岁自闭症儿童患小儿坏血病的病例,该儿童饮食受限,出现拒绝行走、疲劳、紫癜性皮疹和牙龈出血症状。诊断基于饮食史、体格检查结果以及补充维生素C后症状缓解。我们的病例报告重申维生素C缺乏症仍然存在,对于饮食受限的儿童应予以考虑。医生对这种疾病的早期识别可实现早期诊断,避免昂贵的诊断检查和住院治疗,并加快有效治疗。