Martínez-García Mireya, Salinas-Ortega Magaly, Estrada-Arriaga Iván, Hernández-Lemus Enrique, García-Herrera Rodrigo, Vallejo Maite
Sociomedical Research Department, National Institute of Cardiology, Mexico City, Mexico.
Metropolitan Autonomous University (UAM), Xochimilco, Mexico City, Mexico.
PLoS One. 2018 Jan 25;13(1):e0190960. doi: 10.1371/journal.pone.0190960. eCollection 2018.
Cardiovascular diseases are the leading cause of human mortality worldwide. Among the many factors associated with the etiology, incidence, and evolution of such diseases; social and environmental issues constitute an important and often overlooked component. Understanding to a greater extent the scope to which such social determinants of cardiovascular diseases (SDCVD) occur as well as the connections among them would be useful for public health policy making. Here, we will explore the historical trends and associations among the main SDCVD in the published literature. Our aim will be finding meaningful relations among those that will help us to have an integrated view on this complex phenomenon by providing historical context and a relational framework. To uncover such relations, we used a data mining approach to the current literature, followed by network analysis of the interrelationships discovered. To this end, we systematically mined the PubMed/MEDLINE database for references of published studies on the subject, as outlined by the World Health Organization's framework on social determinants of health. The analyzed structured corpus consisted in circa 1190 articles categorized by means of the Medical Subheadings (MeSH) content-descriptor. The use of data analytics techniques allowed us to find a number of non-trivial connections among SDCVDs. Such relations may be relevant to get a deeper understanding of the social and environmental issues associated with cardiovascular disease and are often overlooked by traditional literature survey approaches, such as systematic reviews and meta-analyses.
心血管疾病是全球人类死亡的主要原因。在与这些疾病的病因、发病率和演变相关的众多因素中，社会和环境问题是一个重要且常常被忽视的组成部分。更深入地了解心血管疾病的社会决定因素（SDCVD）的范围及其相互之间的联系，将有助于制定公共卫生政策。在此，我们将探讨已发表文献中主要SDCVD的历史趋势及其之间的关联。我们的目标是找出那些有意义的关系，通过提供历史背景和关系框架，帮助我们对这一复杂现象有一个综合的认识。为了揭示这些关系，我们对当前文献采用了数据挖掘方法，随后对发现的相互关系进行网络分析。为此，我们按照世界卫生组织关于健康的社会决定因素的框架，系统地在PubMed/MEDLINE数据库中挖掘关于该主题的已发表研究的参考文献。所分析的结构化语料库包括大约1190篇通过医学主题词表（MeSH）内容描述符分类的文章。数据分析技术的使用使我们能够在SDCVD之间找到一些重要的联系。这些关系可能有助于更深入地理解与心血管疾病相关的社会和环境问题，而传统的文献综述方法，如系统评价和荟萃分析，往往会忽略这些问题。
