Division of Primary Care and Population Health, Department of Medicine, School of Medicine, Stanford University, Stanford, California.
Department of Obstetrics and Gynecology, School of Medicine, Stanford University, Stanford, California.
Am J Epidemiol. 2018 Apr 1;187(4):687-695. doi: 10.1093/aje/kwy003.
With increasing integration of women into combat roles in the US military, it is critical to determine whether deployment, which entails unique stressors and exposures, is associated with adverse reproductive outcomes. Few studies have examined whether deployment increases the risk of preterm birth; no studies (to our knowledge) have examined a recent cohort of servicewomen. We therefore used linked medical and administrative data from the Stanford Military Data Repository for all US Army soldiers with deliveries between 2011 and 2014 to estimate the associations of prior deployment, recency of deployment, and posttraumatic stress disorder with spontaneous preterm birth (SPB), adjusting for sociodemographic, military-service, and health-related factors. Of 12,877 deliveries, 6.1% were SPBs. The prevalence was doubled (11.7%) among soldiers who delivered within 6 months of their return from deployment. Multivariable discrete-time logistic regression models indicated that delivering within 6 months of return from deployment was strongly associated with SPB (adjusted odds ratio = 2.1, 95% confidence interval: 1.5, 2.9). Neither multiple past deployments nor posttraumatic stress disorder was significantly associated with SPB. Within this cohort, timing of pregnancy in relation to deployment was identified as a novel risk factor for SPB. Increased focus on servicewomen's pregnancy timing and predeployment access to reproductive counseling and effective contraception is warranted.
随着女性在美国军队中参与战斗角色的不断增加,确定部署是否与不良生殖结果相关至关重要。很少有研究探讨部署是否会增加早产的风险;据我们所知,没有研究调查过最近的一批女兵。因此,我们使用斯坦福军事数据资源库中的医疗和行政数据,对 2011 年至 2014 年间所有分娩的美国陆军士兵进行了分析,以评估先前的部署、最近的部署以及创伤后应激障碍与自发性早产(SPB)之间的关联,调整了社会人口统计学、兵役和与健康相关的因素。在 12877 次分娩中,6.1%是 SPB。在部署返回后 6 个月内分娩的士兵中,这一比例增加了一倍(11.7%)。多变量离散时间逻辑回归模型表明,从部署返回后 6 个月内分娩与 SPB 密切相关(调整后的优势比=2.1,95%置信区间:1.5,2.9)。多次过去的部署或创伤后应激障碍都与 SPB 没有显著关联。在这个队列中,怀孕与部署的时间关系被确定为 SPB 的一个新的危险因素。需要更加关注女兵的怀孕时间,并在部署前提供生殖咨询和有效的避孕措施。