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精准健康:利用组学优化老年人慢性疼痛的自我管理。

Precision Health: Use of Omics to Optimize Self-Management of Chronic Pain in Aging.

作者信息

Dorsey Susan G, Resnick Barbara M, Renn Cynthia L

出版信息

Res Gerontol Nurs. 2018 Jan 1;11(1):7-13. doi: 10.3928/19404921-20171128-01.

DOI:10.3928/19404921-20171128-01
PMID:29370441
Abstract

Chronic pain has become a public health epidemic based on the number of Americans affected and its associated health care costs. Unfortunately, there are few efficacious treatments to manage chronic pain and as the population of older adults and centenarians who are at high risk for chronic pain continues to grow, the chronic pain epidemic will continue to worsen unless new therapeutic strategies are discovered. In the current era of precision medicine, there is a major emphasis being placed on the use of self-management and omics to discover new therapeutic targets and design treatment strategies that are tailored to the individual patient. This commentary discusses the current state of the science related to omics and self-management of chronic pain in older adults, the role of gerontological nurses in this process, and future directions. [Res Gerontol Nurs. 2018; 11(1):7-13.].

摘要

基于受影响的美国人数量及其相关医疗保健成本,慢性疼痛已成为一种公共卫生流行病。不幸的是,用于管理慢性疼痛的有效治疗方法很少,而且随着慢性疼痛高风险的老年人和百岁老人数量持续增长,除非发现新的治疗策略,慢性疼痛流行病将继续恶化。在当前的精准医学时代,人们主要强调利用自我管理和组学来发现新的治疗靶点,并设计针对个体患者的治疗策略。本评论讨论了与老年人慢性疼痛的组学和自我管理相关的科学现状、老年护理护士在此过程中的作用以及未来方向。[《老年护理研究》。2018年;11(1):7 - 13。]

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