Luo Han, Zhao Wanjun, Yang Hongliu, Han Qianqian, Zeng Li, Tang Huairong, Zhu Jingqiang
Department of Thyroid & Parathyroid surgery, West China Hospital, Sichuan University, West China Hospital, Guoxue Alley 37#, Chengdu, Sichuan, People's Republic of China, Postal code: 610041.
Department of Nephrology, West China Hospital, Sichuan University, Sichuan, Chengdu, People's Republic of China.
BMC Womens Health. 2018 Jan 25;18(1):26. doi: 10.1186/s12905-017-0465-0.
There is dearth of research about female sexual dysfunction (FSD), especially in China, because of conservative beliefs. Previous studies indicated the relationship between subclinical hypothyroidism and anxiety and depression. However, there is dearth of research regarding the relationship between subclinical hypothyroidism and FSD in Chinses women.
A hospital-based research was conducted. Female sexual function was measured by CVFSFI which includes 19 items. Participants were identified as FSD if CVFSFI ≤ 23.45. Logistics analysis was used to determine risk factor of FSD. All of them finished CVFSFI, Beck Depression Inventory (BDI) self-reporting questionnaires and had thyroid hormone tests. Based on presence and absence of subclinical hypothyroidism, participants were divided into two groups. Risk factors of FSD were identified.
One thousand one hundred nineteen participants with CVFSFI score 25.8 ± 3.9 were enrolled in final analysis. Incidence of subclinical hypothyroidism and FSD in Chinese women was 15.0% and 26.5% respectively. There were no significant difference between subclinical hypothyroidism and control group in FSFI score and prevalence of FSD. Age, Depression (medium risk) was identified as risk factors for nearly all types of FSD, and Income (ranges from 40,000 to 100,000 RMB/year) as protective factor. Subclinical hypothyroidism had no significant relationship with FSD.
Subclinical hypothyroidism is not the risk factor for FSD in urban women of China.
由于观念保守,关于女性性功能障碍(FSD)的研究匮乏,尤其是在中国。既往研究表明亚临床甲状腺功能减退与焦虑和抑郁之间存在关联。然而,在中国女性中,关于亚临床甲状腺功能减退与FSD之间关系的研究较少。
开展一项基于医院的研究。采用包含19个条目的中国女性性功能量表(CVFSFI)来测量女性性功能。如果CVFSFI≤23.45,则将参与者认定为患有FSD。采用Logistic分析来确定FSD的危险因素。所有参与者均完成了CVFSFI、贝克抑郁量表(BDI)自填式问卷并进行了甲状腺激素检测。根据是否存在亚临床甲状腺功能减退,将参与者分为两组。确定FSD的危险因素。
1119名CVFSFI评分为25.8±3.9的参与者纳入最终分析。中国女性中亚临床甲状腺功能减退和FSD的发生率分别为15.0%和26.5%。亚临床甲状腺功能减退组与对照组在FSFI评分和FSD患病率方面无显著差异。年龄、抑郁(中度风险)被确定为几乎所有类型FSD的危险因素,收入(每年4万至10万元人民币)为保护因素。亚临床甲状腺功能减退与FSD无显著关系。
亚临床甲状腺功能减退不是中国城市女性FSD的危险因素。