如何进行诊断影像学研究的系统评价和荟萃分析。
How to Perform a Systematic Review and Meta-analysis of Diagnostic Imaging Studies.
机构信息
Department of Radiology, University of Michigan, B1 132G Taubman Center/5302, 1500 East Medical Center Drive, Ann Arbor, MI 48109.
Department of Radiology, University of Michigan, B1 132G Taubman Center/5302, 1500 East Medical Center Drive, Ann Arbor, MI 48109.
出版信息
Acad Radiol. 2018 May;25(5):573-593. doi: 10.1016/j.acra.2017.12.007. Epub 2018 Jan 19.
A systematic review is a comprehensive search, critical evaluation, and synthesis of all the relevant studies on a specific (clinical) topic that can be applied to the evaluation of diagnostic and screening imaging studies. It can be a qualitative or a quantitative (meta-analysis) review of available literature. A meta-analysis uses statistical methods to combine and summarize the results of several studies. In this review, a 12-step approach to performing a systematic review (and meta-analysis) is outlined under the four domains: (1) Problem Formulation and Data Acquisition, (2) Quality Appraisal of Eligible Studies, (3) Statistical Analysis of Quantitative Data, and (4) Clinical Interpretation of the Evidence. This review is specifically geared toward the performance of a systematic review and meta-analysis of diagnostic test accuracy (imaging) studies.
系统评价是对特定（临床）主题的所有相关研究进行全面搜索、批判性评估和综合，可应用于诊断和筛查成像研究的评估。它可以是对现有文献的定性或定量（荟萃分析）综述。荟萃分析使用统计方法来组合和总结多项研究的结果。在本综述中，概述了在四个领域中执行系统评价（和荟萃分析）的 12 步方法：（1）问题制定和数据获取，（2）合格研究的质量评估，（3）定量数据的统计分析，以及（4）证据的临床解释。本综述专门针对诊断性测试准确性（成像）研究的系统评价和荟萃分析的执行。
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