Nisen P, Medford R, Mansour J, Purucker M, Skalka A, Shapiro L
Proc Natl Acad Sci U S A. 1979 Dec;76(12):6240-4. doi: 10.1073/pnas.76.12.6240.
Inverted repeat DNA sequences of Caulobacter crescentus have been isolated, characterized, and cloned in a bacteriophage lambda vector. Both whole populations and individual clones of these sequences were hybridized to restriction endonuclease-generated fragments of chromosomal DNA isolated from cells that were in different stages of the cell cycle. Some inverted repeat DNA sequences were observed to hybridize to different regions of the chromosomal DNA isolated from the morphologically and biochemically distinct swarmer cell and stalked cell populations. These results suggest that the inverted repeat sequences have the capacity to rearrange and thus be located at different sites on the genomes of the different cell types.
新月柄杆菌的反向重复DNA序列已被分离、表征，并克隆到噬菌体λ载体中。这些序列的整个群体和单个克隆都与从处于细胞周期不同阶段的细胞中分离出的染色体DNA的限制性内切酶产生的片段进行杂交。观察到一些反向重复DNA序列与从形态和生化上不同的游动细胞和柄细胞群体中分离出的染色体DNA的不同区域杂交。这些结果表明，反向重复序列有重排的能力，因此可以位于不同细胞类型基因组的不同位点上。
