Center for Outcomes Research and Evaluation, Yale-New Haven Hospital Yale School of Medicine, New Haven, CT.
Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT.
J Am Heart Assoc. 2018 Jan 26;7(3):e007462. doi: 10.1161/JAHA.117.007462.
The reasons for China's high stroke prevalence are not well understood. The cardiovascular risk factor profiles of China and the United States have not been directly compared in nationally representative population samples.
Using data from the CHARLS (China Health and Retirement Longitudinal Study) and the NHANES (US National Health and Nutrition Examination Survey), we compared cardiovascular risk factors from 2011 to 2012 among people aged 45 to 75 years between the 2 countries (China, 12 654 people; United States, 2607 people): blood pressure, cholesterol, body mass index, waist circumference, fasting plasma glucose, hemoglobin A1c, and high-sensitivity C-reactive protein. Compared with the United States, China had a lower prevalence of hypertension but a higher mean blood pressure and a higher proportion of patients with severe hypertension (≥160/100 mm Hg) (10.5% versus 4.5%). China had substantially lower rates of hypertension treatment (46.8% versus 77.9%) and control (20.3% versus 54.7%). Dyslipidemia was less common in China, but lipid levels were not significantly different because dyslipidemia awareness and control rates in China were 3- and 7-fold lower than US rates, respectively. High-sensitivity C-reactive protein, body mass index, and waist circumference were significantly lower in China than in the United States. Clustering of hypertension with other cardiovascular risk factors was more common in China.
Hypertension is more common in the United States, but blood pressure levels are higher in China, which may be responsible for China's high stroke prevalence. The low rates of awareness, treatment, and control of hypertension provide an exceptional opportunity for China to reduce risk in its population.
中国脑卒中发病率高的原因尚不清楚。中国和美国的心血管危险因素概况尚未在具有代表性的全国性人群样本中进行直接比较。
利用 CHARLS(中国健康与养老追踪调查)和 NHANES(美国国家健康与营养调查)的数据,我们比较了 2011 年至 2012 年间两国(中国,12654 人;美国,2607 人)45 岁至 75 岁人群的心血管危险因素:血压、胆固醇、体重指数、腰围、空腹血糖、糖化血红蛋白和高敏 C 反应蛋白。与美国相比,中国的高血压患病率较低,但平均血压较高,且严重高血压(≥160/100mmHg)患者比例较高(10.5%比 4.5%)。中国的高血压治疗率(46.8%比 77.9%)和控制率(20.3%比 54.7%)明显较低。中国的血脂异常发病率较低,但血脂水平没有显著差异,因为中国的血脂异常知晓率和控制率分别比美国低 3 倍和 7 倍。中国的高敏 C 反应蛋白、体重指数和腰围明显低于美国。中国高血压与其他心血管危险因素的聚集更为常见。
美国的高血压更为常见,但中国的血压水平更高,这可能是中国脑卒中发病率高的原因。中国高血压的知晓率、治疗率和控制率均较低,为中国降低人群风险提供了绝佳机会。