Department of Biochemistry, Oxford University, OX1 3QU, UK.
Curr Biol. 2018 Jan 22;28(2):R77-R79. doi: 10.1016/j.cub.2017.11.066.
Chromosomes are shaped by the combined function of the condensin and cohesin Smc-kleisin complexes. After more than two decades of research in this field, a new study finally sheds light on how these machines might interact with their DNA substrates.
染色体的形状由凝聚蛋白和黏连蛋白 Smc-klleisin 复合物的共同功能决定。经过二十多年的研究，一项新的研究终于揭示了这些机器如何与它们的 DNA 底物相互作用。
