[默克尔细胞在皮肤触觉形成中作用的研究进展]
[Advances in the research of function of Merkel cells in tactile formation of skin].
作者信息
You X, Wei Z R
机构信息
Department of Plastic Surgery, the Affiliated Hospital of Zunyi Medical College, Zunyi, 563000, China.
出版信息
Zhonghua Shao Shang Za Zhi. 2018 Jan 20;34(1):51-54. doi: 10.3760/cma.j.issn.1009-2587.2018.01.010.
Skin is the largest sense organ of human, with many mechanoreceptor cells under epidermis or dermis of skin and Merkel cell is one of them. It has been confirmed that Merkel cells play an important role in the process of mechanical transmission of mammalian soft tactile stimulation. Researches showed that Merkel cells had close relation to tactile formation and functioned by Merkel cell-neurite complexes and ion channels Piezo2. This article reviews Merkel cells and the function, problem and prospect of Merkel cells in tactile formation.
皮肤是人体最大的感觉器官，在皮肤的表皮或真皮之下有许多机械感受器细胞，默克尔细胞就是其中之一。已经证实，默克尔细胞在哺乳动物软触觉刺激的机械传导过程中发挥着重要作用。研究表明，默克尔细胞与触觉形成密切相关，并通过默克尔细胞 - 神经突复合体和Piezo2离子通道发挥作用。本文综述了默克尔细胞以及默克尔细胞在触觉形成中的功能、问题和前景。
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