Sun Qiang, Xie Chenlu, Niu Zhixing, Su Lei, Wang Xi, Fang Zheng, Zhao Junfang, Chen Shuai, Li Xinming, Sun Minglei
Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Institute of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Oncol Lett. 2017 Dec;14(6):6417-6420. doi: 10.3892/ol.2017.7101. Epub 2017 Sep 28.
In the present case report, a rare bilateral carotid body tumor (CBT) and the imaging and pathological features of a CBT are described. In the present report, a rare case of bilateral carotid body tumor, which developed in the bifurcation of the common carotid artery, and the clinical manifestations, imaging and pathological features of this CBT are summarized. The imaging cannot validate the diagnosis; however, imaging identified that the tumor exhibited an intact envelope. Immunohistochemical staining revealed that the tumor cells were strongly positive for cluster of differentiation 56, Syn and protein S-100, moderately positive for transcription factor E3, negative for cytokeratin and epithelial membrane antigen, and partial cells were weakly positive for Desmir (<5%). In view of the clinical and pathological features of the carotid body tumor, surgery is hypothesized to be the optimal treatment and may enable the tumor to be resected completely. Refined surgical techniques provide the security of safe resection and decrease the risk of complications occurring.
在本病例报告中，描述了一例罕见的双侧颈动脉体瘤（CBT）及其影像学和病理学特征。在本报告中，总结了一例罕见的双侧颈动脉体瘤，其发生于颈总动脉分叉处，以及该颈动脉体瘤的临床表现、影像学和病理学特征。影像学检查不能确诊；然而，影像学显示肿瘤包膜完整。免疫组织化学染色显示，肿瘤细胞分化簇56、突触素和S-100蛋白呈强阳性，转录因子E3呈中度阳性，细胞角蛋白和上皮膜抗原呈阴性，部分细胞结蛋白呈弱阳性（<5%）。鉴于颈动脉体瘤的临床和病理特征，推测手术是最佳治疗方法，可能使肿瘤完全切除。精细的手术技术为安全切除提供了保障，并降低了并发症发生的风险。
