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多层螺旋CT与MRI对乙型肝炎肝硬化所致小肝癌的诊断研究

Study on the diagnosis of small hepatocellular carcinoma caused by hepatitis B cirrhosis via multi-slice spiral CT and MRI.

作者信息

Wang Mei, Wei Congxin, Shi Zhaojuan, Zhu Jianzhong

机构信息

Department of Radiology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.

Department of Medical Imaging, The Affiliated Hospital of Taishan Medical College, Taian, Shandong 271000, P.R. China.

出版信息

Oncol Lett. 2018 Jan;15(1):503-508. doi: 10.3892/ol.2017.7313. Epub 2017 Oct 31.

Abstract

The present study compared the diagnostic accuracy of multi-slice spiral computed tomography (CT) and magnetic resonance imaging (MRI) on small hepatocellular carcinoma (SHCC) caused by hepatitis B cirrhosis. A total of 160 patients with hepatitis B cirrhosis were selected between January 2012 and April 2016, and 183 SHCC lesions were included in the present retrospective study. Patients were divided into the SHCC group (T stage) and the micro hepatocellular carcinoma (MHCC) group (T1 stage). There were a total of 129 SHCC lesions and 54 MHCC lesions identified. All patients underwent multiphasic CT and MRI imaging. The liver acquisition with volume acquisition (LAVA) technique was utilized for MRI. Furthermore, SPSS 20.0 was used for statistical analyses. LAVA in the arterial phase and CT in the arterial phase revealed significantly higher diagnostic rates for the diagnoses of 183 lesions. In addition, standard CT scan exhibited significantly reduced diagnostic rates in SHCC lesions. Results indicated that LAVA in the equilibrium phase had the lowest diagnostic rate in MHCC lesions, which was statistically significant (P<0.05). Overall, the diagnostic rate of CT (79.63%) for MHCC was significantly lower than that of MRI (96.29%) (P<0.05). However, the diagnostic rate of CT for SHCC (96.12%) was significantly higher than that for MHCC (79.63%) (P<0.05). MRI-LAVA in the arterial phase has the highest diagnostic rate for SHCC and MHCC. However, the diagnostic capability of MRI for MHCC lesions is superior to that of CT.

摘要

本研究比较了多层螺旋计算机断层扫描(CT)和磁共振成像(MRI)对乙型肝炎肝硬化所致小肝癌(SHCC)的诊断准确性。2012年1月至2016年4月共选取160例乙型肝炎肝硬化患者,本回顾性研究纳入183个SHCC病灶。患者分为SHCC组(T分期)和微小肝细胞癌(MHCC)组(T1分期)。共识别出129个SHCC病灶和54个MHCC病灶。所有患者均接受了多期CT和MRI成像检查。MRI采用容积采集肝脏采集(LAVA)技术。此外,使用SPSS 20.0进行统计分析。LAVA动脉期和CT动脉期对183个病灶的诊断率显著更高。此外,标准CT扫描对SHCC病灶的诊断率显著降低。结果表明,LAVA平衡期对MHCC病灶的诊断率最低,差异有统计学意义(P<0.05)。总体而言,CT对MHCC的诊断率(79.63%)显著低于MRI(96.29%)(P<0.05)。然而,CT对SHCC的诊断率(96.12%)显著高于对MHCC的诊断率(79.63%)(P<0.05)。MRI-LAVA动脉期对SHCC和MHCC的诊断率最高。然而,MRI对MHCC病灶的诊断能力优于CT。

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