Nojima Y, Terai C, Takano K, Takehara K, Yamada A, Takaku F
Clin Nephrol. 1986 Jan;25(1):48-51.
We report a patient who suffered from cutaneous vasculitis with renal involvement comprising tubulointerstitial (TI) nephritis and relatively mild glomerulitis. Renal biopsy revealed immune deposits both in mesangium and along tubular basement membrane (TBM), suggesting that immune complexes played a significant role in the development of renal damage. Although it is well known that vasculitic syndromes commonly affect glomeruli, this report is the first to demonstrate tubulointerstitial immune complex nephritis in a patient with cutaneous vasculitis.
我们报告了一名患有皮肤血管炎并累及肾脏的患者,其肾脏病变包括肾小管间质性(TI)肾炎和相对较轻的肾小球炎。肾活检显示系膜和肾小管基底膜(TBM)均有免疫沉积物,提示免疫复合物在肾损伤的发生中起重要作用。虽然血管炎综合征通常累及肾小球已广为人知,但本报告首次在一名皮肤血管炎患者中证实了肾小管间质性免疫复合物肾炎。