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原发性心脏高级别黏液纤维肉瘤伴多发脑转移:一例报告

Primary Cardiac High-grade Myxofibrosarcoma Presenting with Multiple Brain Metastases: A Case Report.

作者信息

Badaloni Filippo, Pozzati Eugenio, Marucci Gianluca, Fiaschi Pietro, Fioravanti Antonio

机构信息

Department of Neurosurgery, IRCCS Institute of Neurological Sciences of Bologna, Bellaria Hospital, Bologna, Italy.

Neuropathology Unit, IRCCS Foundation "carlo Besta" Neurological Institute, Milan, Italy.

出版信息

Cureus. 2017 Nov 21;9(11):e1866. doi: 10.7759/cureus.1866.

Abstract

Herein we describe the case of a young patient who presented with a recent history of epilepsy due to multiple brain lesions; he did not complain about any cardiopulmonary impairments. The patient died as a consequence of hemorrhagic progression of brain metastatic disease. Regardless of a thorough investigation, the heart tumor remained occult. Primary cardiac tumors are very rare entities. Most of these are benign, but approximately 25% are malignant, and the majority of these are sarcomas. Myxofibrosarcoma and osteosarcoma are exceptionally rare. To date, we find only small series of cardiac myxofibrosarcoma, and to our knowledge, this one exceptionally presented with multiple brain metastatic lesions without cardiopulmonary symptoms.

摘要

在此,我们描述了一名年轻患者的病例,该患者近期因多发性脑病变出现癫痫病史;他未诉说任何心肺功能障碍。患者因脑转移性疾病的出血进展而死亡。尽管进行了全面检查,心脏肿瘤仍未被发现。原发性心脏肿瘤是非常罕见的实体。其中大多数是良性的,但约25%是恶性的,且其中大多数是肉瘤。黏液纤维肉瘤和骨肉瘤极为罕见。迄今为止,我们仅发现少量关于心脏黏液纤维肉瘤的病例系列,据我们所知,该病例特别之处在于出现多发性脑转移病变且无心肺症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fd3/5773267/2fbdd8462360/cureus-0009-00000001866-i01.jpg

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