Devbhandari Mohan P, Meraj Shaista, Jones Mark T, Kadir Isaac, Bridgewater Ben
Department of Cardiothoracic Surgery, Wythenshawe Hospital,Manchester, UK, M23 9LT.
J Cardiothorac Surg. 2007 Jul 24;2:34. doi: 10.1186/1749-8090-2-34.
Primary cardiac sarcomas are rare tumors with an unfavourable prognosis. Complete surgical resection is currently the only mode of therapy proven to show any benefit. We report the cases of two patients presenting with features of obstruction and embolism and a presumed diagnosis of left atrial myxoma. At operation they were unexpectedly found to have large tumours raising strong suspicions of malignancy. Due to the extensive involvement of intracardiac structures with little possibility of reconstruction together with poor general condition of the patient, debulking was deemed to be the only viable option. Subsequent histology confirmed the diagnosis of sarcoma in both patients. Surgery produced immediate and effective symptom relief. The first patient died four months after the operation and second patient is still alive at 12 months after her operation. A brief review of literature on cardiac sarcoma is presented.
原发性心脏肉瘤是一种罕见肿瘤，预后不良。目前，完整的手术切除是唯一经证实有治疗益处的治疗方式。我们报告了两例表现为梗阻和栓塞特征且初步诊断为左心房黏液瘤的患者病例。手术时意外发现他们患有大肿瘤，高度怀疑为恶性肿瘤。由于心脏内结构广泛受累，重建可能性小，且患者一般状况较差，减瘤手术被认为是唯一可行的选择。随后的组织学检查证实两名患者均为肉瘤。手术立即有效缓解了症状。第一名患者术后四个月死亡，第二名患者术后12个月仍然存活。本文对心脏肉瘤的文献进行了简要综述。
