Kim Hoon, Kim Seul Ki, Lee Jung Ryeol, Hwang Kyung Joo, Suh Chang Suk, Kim Seok Hyun
Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.
Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Korea.
Clin Exp Reprod Med. 2017 Dec;44(4):181-186. doi: 10.5653/cerm.2017.44.4.181. Epub 2017 Dec 31.
With advances in the methods of cancer treatment used in modern medicine, the number of breast cancer survivors has been consistently rising. As the number of women who wish to become pregnant after being diagnosed with breast cancer increases, it is necessary to consider fertility preservation in these patients. However, medical doctors may be unaware of the importance of fertility preservation among cancer patients because most patients do not share their concerns about fertility with their doctors. Considering the time spent choosing and undergoing treatment, an early referral to a reproductive specialist is the best way to prevent a delay in cancer treatment. Since it is not easy to make decisions on matters related to cancer diagnosis and fertility, patients should be provided with enough time for decision-making, and to allow for this, an early referral will provide patients with sufficient time to choose an appropriate method of fertility preservation. The currently available options of fertility preservation for patients with breast cancer include cryopreservation of embryos, oocytes, and ovarian tissue and gonadotropin-releasing hormone agonist treatment before and during chemotherapy. An appropriate method of fertility preservation must be selected through consultations between individual patients and health professionals and analyses of the pros and cons of different options.
随着现代医学中癌症治疗方法的进步,乳腺癌幸存者的数量一直在持续上升。随着被诊断出患有乳腺癌后希望怀孕的女性数量增加,有必要考虑对这些患者进行生育力保存。然而,医生可能没有意识到癌症患者生育力保存的重要性,因为大多数患者不会与医生分享他们对生育力的担忧。考虑到选择和接受治疗所花费的时间,尽早转诊至生殖专家是防止癌症治疗延误的最佳方法。由于就癌症诊断和生育力相关事宜做出决定并不容易,应给予患者足够的时间进行决策,为此,尽早转诊将为患者提供足够的时间来选择合适的生育力保存方法。目前乳腺癌患者可用的生育力保存选项包括胚胎、卵母细胞和卵巢组织的冷冻保存以及化疗前和化疗期间的促性腺激素释放激素激动剂治疗。必须通过个体患者与健康专业人员之间的咨询以及对不同选项利弊的分析来选择合适的生育力保存方法。